A
Arnold Mittelman
Researcher at Roswell Park Cancer Institute
Publications - 151
Citations - 5091
Arnold Mittelman is an academic researcher from Roswell Park Cancer Institute. The author has contributed to research in topics: Colorectal cancer & Carcinoma. The author has an hindex of 35, co-authored 151 publications receiving 5043 citations. Previous affiliations of Arnold Mittelman include University at Buffalo.
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Journal ArticleDOI
Diet in the Epidemiology of Cancer of the Colon and Rectum
TL;DR: The decrease in risk the authors found associated with frequent ingestion of vegetables, and especially cabbage, Brussels sprouts, and broccoli, is consistent with the decreased numbers of tumors observed in animals challenged with carcinogens and fed compounds found in these same vegetables.
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A prospective randomized trial of 5-fluorouracil versus 5-fluorouracil and high-dose leucovorin versus 5-fluorouracil and methotrexate in previously untreated patients with advanced colorectal carcinoma.
Nicholas J. Petrelli,Lemuel Herrera,Youcef M. Rustum,P Burke,Patrick J. Creaven,J P Stulc,Lawrence J. Emrich,Arnold Mittelman +7 more
TL;DR: Previously untreated patients with metastatic colorectal adenocarcinoma were prospectively randomized into one of three treatment regimens, and the predominant toxicity in the 5-FU alone regimen and the5-FU and MTX regimen was leukopenia.
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Metastases in Small Lymph Nodes From Colon Cancer
Lemuel Herrera-Ornelas,Jorge Justiniano,Nieva B. Castillo,Nicholas J. Petrelli,Jaroslav P. Stulc,Arnold Mittelman +5 more
TL;DR: It is concluded that lymph node metastases in colon cancer occur most frequently in lymph nodes measuring less than 5 mm (small lymph nodes), and the use of lymph node clearing techniques in surgical specimens improves detection of small lymph nodes metastases and thereby diminishes understaging.
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Dietary epidemiology of cancer of the colon in western new york
Saxon Graham,James Marshal,Brenda P. Haughey,Arnold Mittelman,Mya Swanson,Maria Zielezny,Tim Byers,Gregg Wilkinson,Dee W. West +8 more
TL;DR: The authors interviewed 428 pathologically confirmed cases of colon cancer and controls matched on age, sex, race, and neighborhood in the New York counties containing the cities of Buffalo, Niagara Falls, and Rochester to find the risk to increase with increases in the Quetelet index of relative weight.
Journal Article
Phase I-II Trial of High-Dose Calcium Leucovorin and 5-Fluorouracil in Advanced Colorectal Cancer
S. Madajewicz,Nicholas J. Petrelli,Youcef M. Rustum,Joel Campbell,Lemuel Herrera,Arnold Mittelman,April Perry,Patrick J. Creaven +7 more
TL;DR: 5-FURA-CF appears to be effective in patients clinically resistant to 5-FUra, and this study is being extended to randomized trial of 5-Fura-CF versus 5-UFra alone.