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Asela Weerawardhana
Researcher at Chungnam National University
Publications - 3
Citations - 31
Asela Weerawardhana is an academic researcher from Chungnam National University. The author has contributed to research in topics: Pattern recognition receptor & Innate immune system. The author has an hindex of 1, co-authored 3 publications receiving 1 citations.
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Regulation of antiviral innate immune signaling and viral evasion following viral genome sensing.
TL;DR: Lee et al. as mentioned in this paper focused on the current state of knowledge regarding key host factors that regulate innate immune signaling molecules upon viral infection and discussed evidence showing how specific viral proteins counteract antiviral responses via immunomodulatory strategies.
Journal ArticleDOI
Inhibitory Effect of Sargassum fusiforme and Its Components on Replication of Respiratory Syncytial Virus In Vitro and In Vivo
Kiramage Chathuranga,Asela Weerawardhana,Niranjan Dodantenna,Lakmal Ranathunga,Won-Kyung Cho,Jin Yeul Ma,Jong-Soo Lee +6 more
TL;DR: Sargassum fusiforme extract (SFE) has antiviral effects against respiratory syncytial virus (RSV) in vitro and in vivo mouse model.
Journal ArticleDOI
Inhibition of MAVS Aggregation-Mediated Type-I Interferon Signaling by Foot-and-Mouth Disease Virus VP3.
Pathum Ekanayaka,Byeong-Hoon Lee,Asela Weerawardhana,Kiramage Chathuranga,Jong-Hyeon Park,Jong-Soo Lee +5 more
TL;DR: In this paper, the authors describe the specificity of FMDV VP3 interaction with the transmembrane (TM) domain of MAVS for its effective replication, and they provide a clear understanding of a key molecular mechanism used by the FMDVM VP3 for the suppression of IFN responses via targeting MAVS.