A
Aya M. El-Seidy
Researcher at Alexandria University
Publications - 2
Citations - 56
Aya M. El-Seidy is an academic researcher from Alexandria University. The author has contributed to research in topics: Pyrazole & Antimalarial Agent. The author has an hindex of 2, co-authored 2 publications receiving 29 citations.
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Synthesis, in silico experiments and biological evaluation of 1,3,4-trisubstituted pyrazole derivatives as antimalarial agents
Adnan A. Bekhit,Adnan A. Bekhit,Manal N. S. Saudi,Ahmed M. M. Hassan,Salwa M. Fahmy,Tamer M. Ibrahim,Doaa A. Ghareeb,Aya M. El-Seidy,Sherry N. Nasralla,Alaa El-Din A. Bekhit +9 more
TL;DR: New 1,3,4-trisubstituted pyrazole derivatives were synthesized and evaluated for their antiplasmodial activity and molecular docking of the most active compounds against the wildtype and quadruple mutant pf DHFR-TS structures rationalized the in vitro antimalarial activity.
Journal ArticleDOI
Synthesis, molecular modeling and biological screening of some pyrazole derivatives as antileishmanial agents
Adnan A. Bekhit,Adnan A. Bekhit,Manal N. S. Saudi,Ahmed Mm Hassan,Salwa M. Fahmy,Tamer M. Ibrahim,Doaa A. Ghareeb,Aya M. El-Seidy,Sayed Mahmood Alqallaf,Huda J Habib,Alaa El-Din A. Bekhit +10 more
TL;DR: This study offers promising entities for antileishmanial activity and drug-likeness and toxicity predictions showed acceptable profiles for most of the compounds, which were validated by experimental toxicity studies.