A
Azam Mohammed
Researcher at Boston Children's Hospital
Publications - 1
Citations - 1474
Azam Mohammed is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: ABL & Chronic myelogenous leukemia. The author has an hindex of 1, co-authored 1 publications receiving 1420 citations.
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Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl
Ellen Weisberg,Paul W. Manley,Werner Breitenstein,Josef Brüggen,Sandra W. Cowan-Jacob,Arghya Ray,Brian J. P. Huntly,Doriano Fabbro,Gabriele Fendrich,Elizabeth Hall-Meyers,Andrew L. Kung,Andrew L. Kung,Jürgen Mestan,George Q. Daley,Linda Callahan,Laurie Catley,Cara Cavazza,Azam Mohammed,Donna Neuberg,Renee D. Wright,D. Gary Gilliland,James D. Griffin +21 more
TL;DR: AMN107 prolonged survival of mice injected with Bcr-Abl-transformed hematopoietic cell lines or primary marrow cells, and prolonged survival in imatinib-resistant CML mouse models, suggests this is a promising new inhibitor for the therapy of CML and Ph+ ALL.