B
B. Baker
Researcher at Mayo Clinic
Publications - 4
Citations - 503
B. Baker is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Insulin & Insulin receptor. The author has an hindex of 4, co-authored 4 publications receiving 482 citations.
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Journal ArticleDOI
Production of insulin resistance by hyperinsulinaemia in man.
TL;DR: The results indicate that hyperinsulinaemia of the magnitude observed in insulin resistant states, such as obesity, can produce insulin resistance in man.
Journal ArticleDOI
Effect of thyroid hormone excess on action, secretion, and metabolism of insulin in humans.
George Dimitriadis,B. Baker,H. M. Marsh,Lawrence J. Mandarino,Robert A. Rizza,Richard N. Bergman,Morey W. Haymond,John E. Gerich +7 more
TL;DR: Insulin-induced suppression of glucose production was impaired, and submaximal rates of nonoxidative glucose disposal and glucose uptake were inappropriately low for the increased insulin receptor binding.
Journal ArticleDOI
Infusion of insulin impairs human adipocyte glucose metabolism in vitro without decreasing adipocyte insulin receptor binding
TL;DR: The discordant effect of hyperinsulinaemia on monocyte and adipocytes insulin binding indicates that monocyte insulin binding may not always reflect insulin binding in insulin-sensitive tissues.
Journal ArticleDOI
Influence of Changes in Insulin Receptor Binding during Insulin Infusions on the Shape of the Insulin Dose-Response Curve for Glucose Disposal in Man*
TL;DR: Results indicate that although monocyte insulin binding decreased during dose-response experiments using sequential infusions of insulin, due to the concentrations of insulin at which this occurs this decrease did not alter the shape of the dose- response curve relating glucose disposal to monocytes insulin receptor occupancy.