B
B. Delaloye
Researcher at University Hospital of Lausanne
Publications - 27
Citations - 931
B. Delaloye is an academic researcher from University Hospital of Lausanne. The author has contributed to research in topics: Immunoscintigraphy & Monoclonal antibody. The author has an hindex of 14, co-authored 27 publications receiving 920 citations. Previous affiliations of B. Delaloye include University of Lausanne.
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Journal ArticleDOI
Detection of colorectal carcinoma by emission-computerized tomography after injection of 123I-labeled Fab or F(ab')2 fragments from monoclonal anti-carcinoembryonic antigen antibodies.
B. Delaloye,Angelika Bischof-Delaloye,F. Buchegger,V von Fliedner,J. P. Grob,J. C. Volant,J. Pettavel,J P Mach +7 more
TL;DR: The contrast of the tumor images obtained with Fab fragments suggests that this improved method of immunoscintigraphy has the potential to detect early tumor recurrences and thus to increase the survival of patients.
Journal Article
Clinical Value of Immunoscintigraphy in Colorectal Carcinoma Patients: A Prospective Study
Angelika Bischof-Delaloye,B. Delaloye,Franz Buchegger,Willy Gilgien,A. Studer,S. Curchod,Jean-Claude Givel,François Mosimann,Jacques Pettavel,Jean-Pierre Mach +9 more
TL;DR: Radioimmunoscintigraphy with ECT and 123I-labeled anti-CEA MAb allows early detection of recurrence or metastasis of colorectal cancer and contributes to reduced delay between diagnosis and treatment.
Journal Article
Iodine-131-labeled MAb F(ab')2 fragments are more efficient and less toxic than intact anti-CEA antibodies in radioimmunotherapy of large human colon carcinoma grafted in nude mice
TL;DR: During one week, beginning 18 days after transplantation, nude mice bearing human colon carcinoma were treated by repeated intravenous injections of either iodine-131-(131I) labeled intact antibodies or 131I-labeled corresponding F(ab')2 fragments of a pool of four monoclonal antibodies directed against distinct epitopes of carcinoembryonic antigen (CEA).
Journal ArticleDOI
Loss of psychic self‐activation with bithalamic infarction
TL;DR: Two patients with bilateral thalamo‐mesencephalic infarct in the paramedian territory developed vertical gaze dysfunction and marked behavioural changes, in the absence of significant motor inability and formal neuropsychological impairment.
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Subcortical neglect: Neuropsychological, SPECT, and neuropathological correlations with anterior choroidal artery territory infarction
TL;DR: Single‐photon emission tomography showed that marked hypoperfusion was not limited to the right posterior capsular region, but also involved the overlying parietal cortex, and to a lesser extent the frontal cortex, consistent with a disconnection phenomenon as the basis for subcortical neglect with ipsilateral deactivation of the parietofrontal cortex.