B
B.G. Crampton
Researcher at University of Pretoria
Publications - 38
Citations - 613
B.G. Crampton is an academic researcher from University of Pretoria. The author has contributed to research in topics: Exserohilum & Population. The author has an hindex of 13, co-authored 35 publications receiving 448 citations. Previous affiliations of B.G. Crampton include Council of Scientific and Industrial Research.
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Journal ArticleDOI
In vitro anti-plasmodial activity of Dicoma anomala subsp. gerrardii (Asteraceae): identification of its main active constituent, structure-activity relationship studies and gene expression profiling
John V.W. Becker,Marina M van der Merwe,Marina M van der Merwe,Anna C van Brummelen,Pamisha Pillay,B.G. Crampton,Edwin M. Mmutlane,Christopher J. Parkinson,Fanie R. van Heerden,Neil R. Crouch,Pete Smith,Dalu Mancama,Vinesh Maharaj +12 more
TL;DR: The novel mode of action of dehydrobrachylaenolide, detected during these studies, will play an ongoing role in advancing anti-plasmodial drug discovery efforts.
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Systems genetics reveals a transcriptional network associated with susceptibility in the maize-grey leaf spot pathosystem.
Nanette Christie,Alexander Andrew Myburg,Fourie Joubert,Shane L. Murray,Maryke Carstens,Yao-Cheng Lin,Jacqueline Meyer,B.G. Crampton,Shawn A. Christensen,Jean F. Ntuli,Sara S. Wighard,Yves Van de Peer,Yves Van de Peer,David Kenneth Berger +13 more
TL;DR: This transcriptional network has significant overlap with the GLS susceptibility response of maize line B73, and may reflect pathogen manipulation for nutrient acquisition and/or unsuccessful defence responses, such as kauralexin production by the diterpenoid biosynthesis pathway.
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Physiological responses of selected African sorghum landraces to progressive water stress and re-watering
Natrisha Devnarain,Natrisha Devnarain,B.G. Crampton,Rachel Chikwamba,John V.W. Becker,Martha M. O’Kennedy +5 more
TL;DR: Four previously uncharacterised sorghum genotypes exhibiting drought tolerance are identified and described their physiological responses during water deficit and moderate re-watering.
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Expression of a β-1,3-glucanase from a biocontrol fungus in transgenic pearl millet
M.M. O’Kennedy,B.G. Crampton,M. Lorito,Ereck Chakauya,W.A. Breese,J. T. Burger,Frederik C. Botha +6 more
TL;DR: The event conferring decreased susceptibility to S. graminicola had high levels of the glucanase transcript especially in transgenic plants showing higher levels of downy mildew infection.
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Plasmodium falciparum spermidine synthase inhibition results in unique perturbation-specific effects observed on transcript, protein and metabolite levels
John V.W. Becker,Linda Mtwisha,B.G. Crampton,Stoyan Stoychev,Anna C van Brummelen,Shaun Reeksting,Abraham I. Louw,Lyn-Marie Birkholtz,Dalu Mancama +8 more
TL;DR: This study details the malaria parasite's response to PfSpdSyn inhibition on the transcriptomic, proteomic and metabolic levels and confirms the role of transcriptional regulation in P. falciparum, particularly in this pathway.