Neil R. Crouch

TL;DR: The results of the present study support a rational rather than random approach to the selection of antiplasmodial screening candidates, and identify a number of promising taxa for further investigation as plant-based antimalarial agents.

TL;DR: In vitro toxicity results for Catharanthus roseus, Vinca major, Momordica balsamina and some Sclerocarya birrea extracts raise concern for chronic use.

TL;DR: There is a need for further pharmacological studies on these alkaloids, based on their narcotic-anxiolytic properties, strong synergism with other psychomimetics, moderate toxicity and anti-cancer activity, to be concluded.

TL;DR: A need for greater emphasis on focussed population level research on prioritised medicinal plant species is revealed, including the number of species used, revealing family richness and the degree of endemism, and the Red List Index (RLI) of species survival to measure the relative degree of threat to medicinal species are revealed.

TL;DR: The phytochemical profiles of 38 genera of the Hyacinthaceae will be discussed as well as any biological activity associated with both crude extracts and compounds isolated, and the current contribution considers the family at a global level.