Administration of iproniazid to rabbits in a daily dose of 2 mg/kg for one month increases absorption of I m by the thyroid gland and also increases the concentration of protein-bound iodine in the thyroid and blood plasma. Experimental atherosclerosis , produced by feeding cholesterol to rabbits, lowers the indices of thyroid function, whereas a course of iproniazid given to rabbits with experimental atherosclerosis restores these indices to normal.

B. M. Kopytin

Papers

Effect of the monoamine oxidase inhibitor iproniazid on thyroid function in healthy rabbits with experimental atherosclerosis