B
Balz Frei
Researcher at Boston University
Publications - 60
Citations - 12001
Balz Frei is an academic researcher from Boston University. The author has contributed to research in topics: Lipid peroxidation & Ascorbic acid. The author has an hindex of 40, co-authored 60 publications receiving 11702 citations. Previous affiliations of Balz Frei include University of California & Boston Medical Center.
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Journal ArticleDOI
Ascorbate is an outstanding antioxidant in human blood plasma.
TL;DR: The data demonstrate that ascorbate is the most effective aqueous-phase antioxidant in human blood plasma and suggest that in humans ascorBate is a physiological antioxidant of major importance for protection against diseases and degenerative processes caused by oxidant stress.
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Increase in circulating products of lipid peroxidation (F2-isoprostanes) in smokers. Smoking as a cause of oxidative damage.
Jason D. Morrow,Balz Frei,A W Longmire,J M Gaziano,Sean M. Lynch,Yu Shyr,William Strauss,John A. Oates,L J Roberts nd +8 more
TL;DR: The increased levels of F2-isoprostanes in the circulation of persons who smoke support the hypothesis that smoking can cause the oxidative modification of important biologic molecules in vivo.
Journal ArticleDOI
Antioxidant defenses and lipid peroxidation in human blood plasma.
TL;DR: The data suggest that in states of leukocyte activation and other types of acute or chronic oxidative stress such a simple regimen as controlled ascorbate supplementation could prove helpful in preventing formation of lipid hydroperoxides, some of which cannot be detoxified by endogenous plasma activities and thus might cause damage to critical targets.
Journal ArticleDOI
Ubiquinol-10 is an effective lipid-soluble antioxidant at physiological concentrations
TL;DR: The data together with previous work on the antioxidant function of ubiquinol reported in the literature strongly suggest that ubiqu inol-10 is an important physiological lipid-soluble antioxidant.
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Ascorbic acid reverses endothelial vasomotor dysfunction in patients with coronary artery disease.
TL;DR: Ascorbic acid reverses endothelial vasomotor dysfunction in the brachial circulation of patients with coronary artery disease and suggests that endothelial dysfunction may respond to antioxidant therapy.