B
Bao Yong
Researcher at Fudan University
Publications - 1
Citations - 177
Bao Yong is an academic researcher from Fudan University. The author has contributed to research in topics: Ubiquitin ligase & Autophagosome. The author has an hindex of 1, co-authored 1 publications receiving 146 citations.
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Acetylated hsp70 and KAP1-mediated Vps34 SUMOylation is required for autophagosome creation in autophagy
Yonghua Yang,Warren Fiskus,Bao Yong,Peter Atadja,Yoshinori Takahashi,Tej K. Pandita,Hong Gang Wang,Kapil N. Bhalla +7 more
TL;DR: This work demonstrates that autophagy-inducing stress increases intracellular levels of acetylated inducible heat shock protein (hsp) 70, which binds to the Beclin-1–Vps34 complex, and highlights a regulatory mechanism of Vps34 activity, which involves acetylation hsp70 and KAP1-dependent SUMOylation of VPS34 bound to BeClin 1.