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Yoshinori Takahashi

Researcher at Pennsylvania State University

Publications -  66
Citations -  10404

Yoshinori Takahashi is an academic researcher from Pennsylvania State University. The author has contributed to research in topics: Autophagy & Autophagosome. The author has an hindex of 28, co-authored 57 publications receiving 8603 citations. Previous affiliations of Yoshinori Takahashi include University of South Florida & Penn State Milton S. Hershey Medical Center.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis.

TL;DR: It is demonstrated that Bif-1 interacts with Beclin 1 through ultraviolet irradiation resistance-associated gene (UVRAG) and functions as a positive mediator of the class III PI(3) kinase (PI( 3)KC3) and observed that B if-1 ablation prolongs cell survival under starvation conditions.
Journal ArticleDOI

The Association of AMPK with ULK1 Regulates Autophagy

TL;DR: Results suggest that AMPK association with ULK1 plays an important role in autophagy induction, at least in part, by phosphorylation of raptor to lift the inhibitory effect of mTOR on the ULK 1 autophagic complex.
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Autophagosomal Membrane Serves as Platform for Intracellular Death-inducing Signaling Complex (iDISC)-mediated Caspase-8 Activation and Apoptosis

TL;DR: An autophagy-dependent mechanism of caspase-8 activation and initiation of the apoptotic cascade in response to SKI-I, a pan-sphingosine kinase inhibitor, and bortezomib, a proteasome inhibitor is demonstrated.