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Barry H. Guze

Researcher at University of California, Los Angeles

Publications -  61
Citations -  5813

Barry H. Guze is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Positron emission tomography & Electroconvulsive therapy. The author has an hindex of 28, co-authored 61 publications receiving 5686 citations. Previous affiliations of Barry H. Guze include University of California, Berkeley & California State University, Fresno.

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Reduction of prefrontal cortex glucose metabolism common to three types of depression.

TL;DR: Using positron emission tomography, cerebral glucose metabolism in drug-free, age- and sex-matched, right-handed patients with unipolar depression, bipolar depression, obsessive-compulsive disorder (OCD) with secondary depression, OCD without major depression, and normal controls is studied.
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Caudate glucose metabolic rate changes with both drug and behavior therapy for obsessive-compulsive disorder.

TL;DR: Right orbital cortex/hem was significantly correlated with ipsilateral Cd/hem and thalamus/hem before treatment but not after, and the differences before and after treatment were significant, suggesting a brain circuit involving these brain regions may mediate obsessive-compulsive disorder symptoms.
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Local Cerebral Glucose Metabolic Rates in Obsessive-Compulsive Disorder: A Comparison With Rates in Unipolar Depression and in Normal Controls

TL;DR: In OCD, metabolic rates were significantly increased in the left orbital gyrus and bilaterally in the caudate nuclei, and cerebral glucose metabolic patterns that differed from controls in both the symptomatic and recovered states.
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Cerebral glucose metabolic rates in nondepressed patients with obsessive-compulsive disorder.

TL;DR: The authors compared 10 nondepressed patients with obsessive-compulsive disorder with 10 normal control subjects of the same sex and similar age for cerebral glucose metabolic rates obtained using positron emission tomography.
Journal Article

Thallium-201 SPECT imaging of brain tumors: methods and results.

TL;DR: The technical considerations of deriving a simple 201Tl index, based on uptake in the tumor normalized to homologous contralateral tissue, from SPECT images of brain tumors, are described and the importance of consistently correcting for tissue attenuation is evaluated.