B
Basil D. Brooke
Researcher at University of the Witwatersrand
Publications - 98
Citations - 4549
Basil D. Brooke is an academic researcher from University of the Witwatersrand. The author has contributed to research in topics: Anopheles & Anopheles gambiae. The author has an hindex of 36, co-authored 92 publications receiving 3935 citations. Previous affiliations of Basil D. Brooke include National Institute of Communicable Diseases & National Health Laboratory Service.
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Journal ArticleDOI
Anopheles funestus resistant to pyrethroid insecticides in South Africa.
K. Hargreaves,Lizette L. Koekemoer,Basil D. Brooke,Richard H. Hunt,J. Mthembu,Maureen Coetzee +5 more
TL;DR: Finding these proportions of pyrethroid‐resistant An.
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Bioassay and biochemical analyses of insecticide resistance in southern African Anopheles funestus (Diptera: Culicidae)
Basil D. Brooke,Kloke G,Richard H. Hunt,Lizette L. Koekemoer,Emmanuel A. Temu,Taylor Me,Small G,Janet Hemingway,Maureen Coetzee +8 more
TL;DR: Insecticide exposure, synergist and biochemical assays conducted on A. funestus suggested that elevated levels of mixed function oxidases were responsible for the detoxification of pyrethroids in resistant mosquitoes in these areas.
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Cuticle thickening associated with pyrethroid resistance in the major malaria vector Anopheles funestus
TL;DR: Cuticle thickness was significantly greater in those samples characterised either as more tolerant or resistant to permethrin exposure compared to those characterised as either less tolerant orpermethrin susceptible, and insecticide susceptible female An.
Journal ArticleDOI
Laboratory selection for and characteristics of pyrethroid resistance in the malaria vector Anopheles funestus.
TL;DR: Biochemical analysis of resistant and susceptible individuals showed increased monooxygenase and glutathione S‐transferase activity but no significant correlation with age of the mosquitoes.
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Evidence of multiple pyrethroid resistance mechanisms in the malaria vector Anopheles gambiae sensu stricto from Nigeria.
T. S. Awolola,O. A. Oduola,Clare Strode,Lizette L. Koekemoer,Lizette L. Koekemoer,Basil D. Brooke,Basil D. Brooke,Hilary Ranson +7 more
TL;DR: The co-occurrence of both resistance mechanisms in a population of An.