Showing papers by "Beatriz S. Parajón-Costa published in 2017"
TL;DR: Cadmium and lead(II) acesulfamate, Cd(C₄H/NO/S)₂·2H/O and Pb(C/H/ NO/S), were prepared by the reaction of acid and metal carbonates in aqueous solution, and characterized by elemental analysis as mentioned in this paper.
Abstract: Cadmium and lead(II) acesulfamate, Cd(C₄H₄NO₄S)₂·2H₂O and Pb(C₄H₄NO₄S)₂, were prepared by the reaction of acesulfamic acid and the respective metal carbonates in aqueous solution, and characterized by elemental analysis. Their crystal structures were determined by single crystal X-ray diffraction methods. The Cd(II) compound crystallizes in the monoclinic space group P2₁/c with Z=4 and the corresponding Pb(II) salt in the triclinic space group P1 with Z=2. In both salts, acesulfamate acts both as a bi-dentate ligand through its nitrogen and carbonyl oxygen atoms and also as a mono-dentate ligand through this same oxygen atom, giving rise to polymeric structures; in the Pb(II) salt the ligand also binds the cation through its sulfoxido oxygen atoms. The FTIR spectra of the compounds were recorded and are briefly discussed. Some comparisons with other related acesulfamate and saccharinate complexes are made.
10 citations
TL;DR: The oxovanadium(IV) complex of oxodiacetic acid (H2ODA) and 2,2'-bipyridine (bipy) of stoichiometry (VO(ODA)( bipy))⋅H2O can be considered as a good candidate to be further investigated in relation to cancer treatment.
Abstract: The oxovanadium(IV) complex of oxodiacetic acid (H2ODA) and 2,2'-bipyridine (bipy) of stoichiometry (VO(ODA)(bipy))⋅H2O, was thoroughly characterized by infrared, Raman and electronic spec- troscopies. The biological activity of the complex on the cell prolifera- tion was tested on osteoblast-like cells (MC3T3E1 osteoblastic mouse calvaria-derived cells and UMR106 rat osteosarcoma-derived cells) in culture. The complex caused inhibition of cellular proliferation in both osteoblast-like cells in culture, but its action was statistically stronger in the tumoral cells. This effect was specially marked with increasing concentrations of the complex. Based on these preliminary biological results, (VO(ODA)(bipy))⋅H2O can be considered as a good candidate to be further investigated in relation to cancer treatment.
8 citations
TL;DR: The crystal structure of aqua lithium 6-methyl-1,2,3,oxathiazine-4(3H)-one, 2.2-dioxide, for short Li(ace)H2O, was determined by X-ray diffraction methods.
Abstract: The crystal structure of aqua lithium 6-methyl-1,2,3,-oxathiazine-4(3H)-one, 2.2-dioxide, for short Li(ace)H2O, was determined by X-ray diffraction methods. It crystallizes in the triclinic P
$$\overline {1}$$
space group with a = 6.1750(9) A, b = 7.3969(9) A, c = 9.016(1) A, α = 105.88(1)°, β = 94.59(1)°, γ = 97.80(1)°, and Z = 2 molecules per unit cell. The crystal structure of Li(ace)H2O sharply departs from the other heavier alkaline-metal acesulfamates, namely the monoclinic isotypic M-ace (M from Na+ to Cs+) family of salts. Lithium is in a distorted LiO4 tetrahedral coordination with acesulfamate carbonyl, sulfoxide and water oxygen atoms. The FTIR spectrum of the new compound was also recorded and is briefly discussed. Some comparisons with other simple acesulfamate salts are also made. The synthesis of aqua lithium acesulfamate, Li(C4H4NO4S)H2O, and its structural characterization by single-crystal X-ray diffractometry are reported. The FTIR spectrum of the salt is analyzed by comparison with data of related compounds.
5 citations