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Becky Hackett
Researcher at Trinity College, Dublin
Publications - 3
Citations - 38
Becky Hackett is an academic researcher from Trinity College, Dublin. The author has contributed to research in topics: Cannabidiol & Chemokine. The author has an hindex of 1, co-authored 2 publications receiving 7 citations.
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Cannabidiol modulation of oxidative stress and signalling
TL;DR: In this paper, a review gathers the latest knowledge regarding the impact of CBD on oxidative signalling, with focus on the proclivity of CBD to regulate antioxidants and control the production of reactive oxygen species.
Journal ArticleDOI
Alpha-galactosylceramide enhances mucosal immunity to oral whole-cell cholera vaccines
Christopher J.H. Davitt,Stephanie Longet,Aqel Albutti,Aqel Albutti,Vincenzo Aversa,Stefan Nordqvist,Becky Hackett,Craig P. McEntee,Mónica Rosa,Ivan Coulter,Michael Lebens,Joshua Tobias,Jan Holmgren,Ed C. Lavelle +13 more
TL;DR: The use of the orally active adjuvant α-Galactosylceramide (α-GalCer) to strongly enhance intestinal bacterium- and toxin-specific IgA responses to the OCV, Dukoral® in C57BL/6 and BALB/c mice is described.
Journal ArticleDOI
Botanically-Derived Δ9-Tetrahydrocannabinol and Cannabidiol, and Their 1:1 Combination, Modulate Toll-like Receptor 3 and 4 Signalling in Immune Cells from People with Multiple Sclerosis
TL;DR: Data herein identify CBD and THC as TLR3 and TLR4 modulating drugs in primary immune cells in vitro, and offers insight on the cellular target(s) of phytocannabinoids in targeting inflammation in the context of MS.