Belén Pintado

TL;DR: Mice derived from embryos cultured with FCS exhibited specific behavioral alterations in anxiety and displayed deficiencies in implicit memories, indicating that long-term programming of postnatal development, growth, and physiology can be affected irreversibly during the preimplantation period of embryo development by suboptimal in vitro culture.

TL;DR: The study of 7 differentially expressed mRNAs known to be involved in developmental process in the embryo suggests roles for apoptosis, oxidative stress, gap junctions, and differentiation in the determination of embryo quality.

TL;DR: The results demonstrate that the relative abundance of the transcripts studied varies throughout the preimplantation period and is strongly influenced by the culture environment, and changes in transcript abundance in blastocyst stage embryos are in many cases a consequence of perturbed transcription earlier in development.

TL;DR: The results indicate that transient mild heat treatment does not affect in the same way the different types of male germ cells and point to a higher sensitivity of spermatocytes to heat exposure and also suggest a different response of X and Y chromosome‐bearing spermatozoa to heat stress that warrants further investigation.

TL;DR: This study is the first to investigate the relationship between the developmental speed of embryos produced in vivo or in vitro and the temporal transcription pattern, and finds that for all the genes analyzed there are differences in mRNA expression between embryos with fast and slow developmental speed produced both in vivo and in vivo.