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Alfonso Gutiérrez-Adán
Researcher at University of California, Davis
Publications - 273
Citations - 12851
Alfonso Gutiérrez-Adán is an academic researcher from University of California, Davis. The author has contributed to research in topics: Blastocyst & Embryo. The author has an hindex of 56, co-authored 255 publications receiving 11604 citations. Previous affiliations of Alfonso Gutiérrez-Adán include Complutense University of Madrid & Ministry of Science and Innovation.
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Journal ArticleDOI
Bovine Embryo Culture in the Presence or Absence of Serum: Implications for Blastocyst Development, Cryotolerance, and Messenger RNA Expression
Dimitrios Rizos,Alfonso Gutiérrez-Adán,S. S. Pérez-Garnelo,J. de la Fuente,Maurice P. Boland,Patrick Lonergan +5 more
TL;DR: It is shown that conditions of postfertilization culture, in particular, the presence of serum in the medium, can affect the speed of embryo development and the quality of the resulting blastocysts.
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Long-term effect of in vitro culture of mouse embryos with serum on mRNA expression of imprinting genes, development, and behavior
Raúl Fernández-González,Pedro Moreira,Ainhoa Bilbao,Adela Jiménez,Miriam Pérez-Crespo,Miguel Ángel Ramírez,Fernando Rodríguez de Fonseca,Belén Pintado,Alfonso Gutiérrez-Adán +8 more
TL;DR: Mice derived from embryos cultured with FCS exhibited specific behavioral alterations in anxiety and displayed deficiencies in implicit memories, indicating that long-term programming of postnatal development, growth, and physiology can be affected irreversibly during the preimplantation period of embryo development by suboptimal in vitro culture.
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Analysis of Differential Messenger RNA Expression Between Bovine Blastocysts Produced in Different Culture Systems: Implications for Blastocyst Quality
Dimitrios Rizos,Patrick Lonergan,Maurice P. Boland,Rosa Arroyo-García,Belén Pintado,J. de la Fuente,Alfonso Gutiérrez-Adán +6 more
TL;DR: The study of 7 differentially expressed mRNAs known to be involved in developmental process in the embryo suggests roles for apoptosis, oxidative stress, gap junctions, and differentiation in the determination of embryo quality.
Journal ArticleDOI
Oocyte and embryo quality: effect of origin, culture conditions and gene expression patterns.
TL;DR: Evidence for an effect of oocyte origin and/or in vitro maturation conditions on the developmental capacity and gene expression patterns in the oocyte is demonstrated and the well-documented effects of post-fertilization culture environment on embryo gene expression and quality are highlighted.
Journal ArticleDOI
Progesterone and conceptus elongation in cattle: a direct effect on the embryo or an indirect effect via the endometrium?
M. Clemente,J. de la Fuente,Trudee Fair,A. Al Naib,Alfonso Gutiérrez-Adán,James F. Roche,Dimitrios Rizos,Patrick Lonergan +7 more
TL;DR: Data provide clear evidence to support the hypothesis that P(4)-induced changes in the uterine environment are responsible for the advancement in conceptus elongation reported previously in cattle and that, interestingly, the embryo does not need to be present during the period of high P( 4) in order to exhibit advanced elongation.