B
Bernard Fisher
Researcher at University of Pittsburgh
Publications - 379
Citations - 70162
Bernard Fisher is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 108, co-authored 377 publications receiving 67479 citations. Previous affiliations of Bernard Fisher include University of Texas Health Science Center at San Antonio & Mercy Medical Center (Baltimore, Maryland).
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Journal ArticleDOI
Effect of preoperative chemotherapy on local-regional disease in women with operable breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-18.
Bernard Fisher,Arleen F. Brown,Eleftherios P. Mamounas,S. Wieand,André Robidoux,Richard G. Margolese,A B Cruz,Edwin R. Fisher,Wickerham Dl,Norman Wolmark,Arthur DeCillis,James L. Hoehn,A W Lees,N V Dimitrov +13 more
TL;DR: Preoperative therapy reduced the size of most breast tumors and decreased the incidence of positive nodes in women with primary breast cancer and should be considered for the initial management of breast tumors judged too large for lumpectomy.
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Eight-Year Results of a Randomized Clinical Trial Comparing Total Mastectomy and Lumpectomy with or without Irradiation in the Treatment of Breast Cancer
Bernard Fisher,Carol K. Redmond,Roger Poisson,Richard G. Margolese,Norman Wolmark,Lawrence Wickerham,Edwin R. Fisher,Melvin Deutsch,Richard M. Caplan,Yosef Pilch +9 more
TL;DR: The observations through eight years are consistent with the findings at five years and that these new findings continue to support the use of lumpectomy in patients with Stage I or II breast cancer, and it is concluded that irradiation reduces the probability of local recurrence of tumor in patients treated with Lumpectomy.
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A Randomized Clinical Trial Evaluating Tamoxifen in the Treatment of Patients with Node-Negative Breast Cancer Who Have Estrogen-Receptor–Positive Tumors
Bernard Fisher,Joseph P. Costantino,Carol K. Redmond,Roger Poisson,Bowman D,Couture J,Nikolay V. Dimitrov,Norman Wolmark,Wickerham Dl,Edwin R. Fisher +9 more
TL;DR: Tamoxifen significantly reduced the rate of treatment failure at local and distant sites, tumors in the opposite breast, and the incidence of tumor recurrence after lumpectomy and breast irradiation and was attained with a low incidence of clinically appreciable toxic effects.
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Ten-year results of a randomized clinical trial comparing radical mastectomy and total mastectomy with or without radiation
Bernard Fisher,Carol K. Redmond,Edwin R. Fisher,M Bauer,Norman Wolmark,Wickerham Dl,Melvin Deutsch,E Montague,Richard G. Margolese,Roger S. Foster +9 more
TL;DR: It is indicated that the location of a breast tumor does not influence the prognosis and that irradiation of internal mammary nodes in patients with inner-quadrant lesions does not improve survival and that the results obtained at five years accurately predict the outcome at 10 years.
Journal ArticleDOI
Twenty-Five-Year Follow-up of a Randomized Trial Comparing Radical Mastectomy, Total Mastectomy, and Total Mastectomy Followed by Irradiation
Bernard Fisher,Jong-Hyeon Jeong,Stewart J. Anderson,John Bryant,Edwin R. Fisher,Norman Wolmark +5 more
TL;DR: The findings validate earlier results showing no advantage from radical mastectomy and fail to show a significant survival advantage from removing occult positive nodes at the time of initial surgery or from radiation therapy.