B
Bernard Fisher
Researcher at University of Pittsburgh
Publications - 379
Citations - 70162
Bernard Fisher is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 108, co-authored 377 publications receiving 67479 citations. Previous affiliations of Bernard Fisher include University of Texas Health Science Center at San Antonio & Mercy Medical Center (Baltimore, Maryland).
Papers
More filters
Journal ArticleDOI
Adjuvant 5-Fluorouracil and Leucovorin With or Without Interferon Alfa-2a in Colon Carcinoma: National Surgical Adjuvant Breast and Bowel Project Protocol C-05
Norman Wolmark,John Bryant,Roy E. Smith,Jean L. Grem,Carmen J. Allegra,David M. Hyams,James N. Atkins,Nikolay V. Dimitrov,Robert H. Oishi,David Prager,Louis Fehrenbacher,Edward H. Romond,Linda H. Colangelo,Bernard Fisher +13 more
TL;DR: The addition of IFN to 5-FU + LV adjuvant therapy confers no statistically significant benefit, but it does increase toxicity.
Journal ArticleDOI
Pathologic findings from the national surgical adjuvant breast project (protocol no. 4) vi. discriminants for five‐year treatment failure
TL;DR: The presence of tumor necrosis, poor tumor differentiation and a tumor size > 4 cm were found by multivariate analyses to influence treatment failure in patients without nodal metastases, and represent important discriminants for the prognosis and the design of treatment schemes and subsequent protocols for patients with breast cancer.
Journal ArticleDOI
Tubulolobular invasive breast cancer: A variant of lobular invasive cancer*
TL;DR: The results of these analyses as well as the morphologic characteristics of these lesions prompt the conclusion that this lesion represents a tubular variant of lobular invasive carcinoma.
Journal Article
Overview of randomized trials comparing radical mastectomy without radiotherapy against simple mastectomy with radiotherapy in breast cancer.
Jack Cuzick,Helen J. Stewart,Richard Peto,Bernard Fisher,S Kaae,H Johansen,J. P. Lythgoe,R J Prescott +7 more
TL;DR: An overview of mortality in the mature randomized trials comparing radical mastectomy without radiotherapy against simple mastectomy with radiotherapy has been conducted, and there was a nonsignificant trend for patients given radiotherapy to do worse after 15 years of follow-up.
Journal ArticleDOI
Biological and clinical considerations regarding the use of surgery and chemotherapy in the treatment of primary breast cancer.
TL;DR: Principles upon which operation and systemic chemotherapy are employed in current trials are presented in this review, and a brief review of information regarding tumor cell kinetics, experiences with adjuvant therapy in animal model systems, and other considerations providing justification for the use of systemic adjUvant chemotherapy has been provided.