Bernard Poutrel

TL;DR: The accumulation of neutrophils and the presence of the chemoattractant complement fragment C5a and of the cytokines interleukin-1β, tumor necrosis factor alpha, and IL-8 in milk after inoculation of S. aureus in lactating bovine udders could help in the design of preventive or curative strategies against chronic mastitis.

TL;DR: The analysis indicates that S. aureus isolated from cows has predominantly a clonal structure and that the highly prevalent agr R III-A1, trap 1 type probably possesses a genetic background which endows it with superior ability to infect the bovine mammary gland.

TL;DR: Cell subpopulations in blood from infected cows were not modified, and changes occurred in infected milk: neutrophils were the main cell population, but they were not in a highly activated state; the CD8+ T-lymphocytes were mainly recruited compared with the CD4+ T.lymphocyte population, suggesting that a humoral response developed, and no change was observed in the gammadelta subset.

TL;DR: Intramammary infusion of antibiotics at dry-off and postmilking teat dipping in goats decreased the rate of new IMI and MSCC, indicating mastitis control practices shown to be efficacious in cows are also effective in goats.

TL;DR: The understanding of the specific and nonspecific immune mechanisms involved in the mammary gland defence against invading bacteria may lead to the development of new vaccines and to the use of cytokines to design immunomodulatory strategies for the control of bovine mastitis.