B
Betül Dortunç
Researcher at Marmara University
Publications - 11
Citations - 432
Betül Dortunç is an academic researcher from Marmara University. The author has contributed to research in topics: Transdermal & Controlled release. The author has an hindex of 7, co-authored 11 publications receiving 407 citations.
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Journal ArticleDOI
Preparation and in vitro evaluation of Eudragit microspheres containing acetazolamide.
S. Haznedar,Betül Dortunç +1 more
TL;DR: Although acetazolamide release rates from Eudragit RS microspheres were very slow and incomplete for all formulations, they were fast from EUDragit RL microsphere formulations.
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Preparation and in vitro evaluation of verapamil HCl and ibuprofen containing carrageenan beads.
Oya Sipahigil,Betül Dortunç +1 more
TL;DR: The objective of this study was to prepare and evaluate carrageenan beads as a controlled release system for a freely water soluble drug verapamil hydrochloride and a slightlyWater soluble drug ibuprofen.
Journal ArticleDOI
Development and In Vitro Evaluation of a Buccoadhesive Pindolol Tablet Formulation
TL;DR: Controlled-release buccoadhesive tablets containing pindolol were prepared and evaluated in order to achieve constant plasma concentrations during the treatment of chronic hypertension and to improve the bioavailability of pINDolol by the avoidance of hepatic first-pass metabolism.
Journal ArticleDOI
Non-Aqueous Emulsions as Vehicles for Capsule Fillings
Kurt H. Bauer,Betül Dortunç +1 more
TL;DR: In this paper, a dissolution rate study of soft gelatin capsules and non-aqueous emulsions was conducted and the results showed that the PEG bases exhibit the lowest recoveries, while the nonaqueous bases have a tendency towards a more favorable gastrointestinal absorption.
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Vascular endothelial growth factor-loaded poly(lactic-co-glycolic acid) microspheres-induced lateral axonal sprouting into the vein graft bridging two healthy nerves: nerve graft prefabrication using controlled release system.
Huseyin Karagoz,Ersin Ulkur,Oya Kerimoğlu,Emine Alarçin,Cihan Sahin,Dilek Akakin,Betül Dortunç +6 more
TL;DR: It was demonstrated that nerve graft can be prefabricated by the controlled delivery of VEGF and that nerve injury occurred initially in the partial incision groups according to the indexes of peroneal and tibial function, it improved gradually.