B
Big-Renape Networks
Publications - 2
Citations - 213
Big-Renape Networks is an academic researcher. The author has contributed to research in topics: Pharmacokinetics & Cancer. The author has an hindex of 2, co-authored 2 publications receiving 109 citations.
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Journal ArticleDOI
Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy for Gastric Cancer With Peritoneal Metastases (CYTO-CHIP study): A Propensity Score Analysis.
Pierre-Emmanuel Bonnot,Guillaume Piessen,Vahan Kepenekian,Evelyne Decullier,Marc Pocard,Bernard Meunier,J.M. Bereder,Karine Abboud,Frédéric Marchal,François Quenet,Diane Goéré,Simon Msika,Catherine Arvieux,Nicolas Pirro,Romuald Wernert,Patrick Rat,Johan Gagnière,Jérémie H. Lefevre,Thomas Courvoisier,Reza Kianmanesh,Delphine Vaudoyer,Michel Rivoire,Pierre Meeus,Guillaume Passot,Olivier Glehen,Fregat,Big-Renape Networks +26 more
TL;DR: Compared with CRSa, CRS-HIPEC improved OS and recurrence-free survival, without additional morbidity or mortality, and may be considered a valuable therapy for strictly selected patients with limited PMs from GC.
Journal ArticleDOI
A phase I dose-escalation study of oxaliplatin delivered via a laparoscopic approach using pressurised intraperitoneal aerosol chemotherapy for advanced peritoneal metastases of gastrointestinal tract cancers.
Frédéric Dumont,Christophe Passot,Jean-Luc Raoul,Vahan Kepenekian,Bénédicte Lelièvre,Michelle Boisdron-Celle,Sandrine Hiret,Hélène Senellart,F Pein,Audrey Blanc-Lapierre,Judith Raimbourg,Emilie Thibaudeau,Olivier Glehen,Big-Renape Networks +13 more
TL;DR: The maximum tolerated dose (MTD) of oxaliplatin during PIPAC is 90 mg/m2 and PK data demonstrate a high tumour concentration and a significant systemic absorption.