Bo Nilson

TL;DR: Although it is possible, from comparative amino acid sequence data, to identify certain VL-framework region residues that account for the selective binding of protein L by kappa I, kappa III, and kappa IV proteins, this interaction is essentially dependent upon the tertiary structural integrity of the kappa chain VL domain.

TL;DR: A symbiotic lactic acid bacterial microbiota in the honey stomach of the honeybee Apis mellifera was found to be composed of several phylotypes of Bifidobacterium and Lactobacillus, and the phylotypes isolated represent seven novel species.

TL;DR: It is demonstrated that it is possible to engineer antibodies and antibody fragments (Fab, Fv) with protein L-binding framework regions, which can then be utilized in aprotein L-based purification protocol.

TL;DR: It is hypothesized that conformational rearrangements of envelope glycoproteins were not optimally triggered following binding, and to overcome these postbinding blocks, a set of chimeric MoMLV-derived envelopes targeted to the Ram-1 phosphate transporter are generated in which the interdomain spacing was varied.

TL;DR: Proteolytic activation of receptor-targeted vectors can provide the basis for a novel two-step targeting strategy that may facilitate efficient targeted in vivo delivery of therapeutic genes.