B
Bob Eisenberg
Researcher at Illinois Institute of Technology
Publications - 129
Citations - 5534
Bob Eisenberg is an academic researcher from Illinois Institute of Technology. The author has contributed to research in topics: Ion & Dielectric. The author has an hindex of 42, co-authored 129 publications receiving 5051 citations. Previous affiliations of Bob Eisenberg include Rush Medical College & University of Illinois at Chicago.
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Journal ArticleDOI
Ion Permeation and Glutamate Residues Linked by Poisson-Nernst-Planck Theory in L-Type Calcium Channels
Wolfgang Nonner,Bob Eisenberg +1 more
TL;DR: The successful prediction of Ca fluxes in this paper demonstrates that ad hoc electrostatic parameters, multiple discrete binding sites, and logistic assumptions of single-file movement are all unnecessary for the prediction of permeation in Ca channels over a wide range of conditions.
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Energy variational analysis of ions in water and channels: Field theory for primitive models of complex ionic fluids
TL;DR: A variational method EnVarA (energy variational analysis) is used that combines Hamilton's least action and Rayleigh's dissipation principles to create a variational field theory that includes flow, friction, and complex structure with physical boundary conditions of ions next to a charged wall.
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Binding and Selectivity in L-Type Calcium Channels:A Mean Spherical Approximation
TL;DR: This study examines the hypothesis that selectivity in this locus is determined by mutual electrostatic screening and volume exclusion between ions and carboxylate oxygens of finite diameters, and predicts Ba(2+)/Ca(2+) and Na(+)/Li(+) competition, and Cl(-) exclusion as observed.
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PNP equations with Steric Effects: a Model of Ion Flow through Channels
TL;DR: Steric PNP combines atomic and macroscales in a computable formulation that allows the calculation of the macroscopic effects of changes in atomic scale structures studied very extensively in channology and molecular biology.
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Permeation through an open channel: Poisson-Nernst-Planck theory of a synthetic ionic channel
TL;DR: In contrast to traditional theories, PNP computes the electric field in the open channel from all of the charges in the system, by a rapid and accurate numerical procedure, and is a theory of the shielding of fixed charge of the channel by mobile charge and by the ionic atmosphere in and near the channel's pore.