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Brian J. Kelly
Researcher at Harvard University
Publications - 6
Citations - 235
Brian J. Kelly is an academic researcher from Harvard University. The author has contributed to research in topics: Poison control & Anxiety. The author has an hindex of 6, co-authored 6 publications receiving 214 citations. Previous affiliations of Brian J. Kelly include University of Massachusetts Amherst & Fitchburg State University.
Papers
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Journal ArticleDOI
Stress, the HPA axis, and nonhuman primate well-being: A review
Melinda A. Novak,Amanda F. Hamel,Brian J. Kelly,Amanda M. Dettmer,Amanda M. Dettmer,Jerrold S. Meyer +5 more
TL;DR: Findings parallel human clinical studies demonstrating that neuropsychiatric disorders may be associated with either increased or decreased activity of the HPA system, depending on the aetiology and manifestation of the disorder and their potential influence in provoking allostatic shifts in system functioning.
Journal ArticleDOI
The anxiogenic drug FG7142 increases self-injurious behavior in male rhesus monkeys (Macaca mulatta).
Christine A. Major,Brian J. Kelly,Melinda A. Novak,Melinda A. Novak,Matthew D. Davenport,Karen M. Stonemetz,Jerrold S. Meyer +6 more
TL;DR: The present findings indicate that self-biting is anxiety-related in some but not all SIB monkeys, suggesting that this behavioral pathology is heterogeneous as has previously been suggested for SIB in humans.
Journal ArticleDOI
TPH2 5'- and 3'-regulatory polymorphisms are differentially associated with HPA axis function and self-injurious behavior in rhesus monkeys.
Guo-Lin Chen,Melinda A. Novak,Melinda A. Novak,Jerrold S. Meyer,Brian J. Kelly,Eric J. Vallender,Gregory M. Miller +6 more
TL;DR: The functionality of rhTPH2 5’‐FR polymorphisms are shown, and evidence is provided for the differential association ofrhTPH 2 5‘‐FR and 3’-UTR polymorphisms with HPA axis function and SIB.
Journal ArticleDOI
The effect of rearing experience and TPH2 genotype on HPA axis function and aggression in rhesus monkeys: a retrospective analysis.
Guo-Lin Chen,Melinda A. Novak,Melinda A. Novak,Jerrold S. Meyer,Brian J. Kelly,Brian J. Kelly,Eric J. Vallender,Gregory M. Miller +7 more
TL;DR: The hypothesis that rearing experience and rhTPH2 A2051C interact to influence central 5-HT metabolism, HPA axis function, and aggressive behaviors is supported.
Book ChapterDOI
Behavioral Disorders of Nonhuman Primates
TL;DR: A number of factors have been shown to increase the risk of developing abnormal behavior, ranging from pacing to self-inflicted wounding in nonhuman primates, such as age of onset, exposure to stressful events, and genetic factors as discussed by the authors.