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Brigitte M. Browe
Researcher at University of Illinois at Chicago
Publications - 7
Citations - 497
Brigitte M. Browe is an academic researcher from University of Illinois at Chicago. The author has contributed to research in topics: Naked mole-rat & Medicine. The author has an hindex of 4, co-authored 5 publications receiving 382 citations.
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Journal ArticleDOI
Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat
Thomas J. Park,Jane Reznick,Bethany L. Peterson,Gregory R.C. Blass,Damir Omerbašić,Nigel C. Bennett,P. Henning J. L. Kuich,Christin Zasada,Brigitte M. Browe,Wiebke Hamann,Daniel T. Applegate,Michael H. Radke,Tetiana Kosten,Heike Lutermann,Victoria M Gavaghan,Ole Eigenbrod,Valérie Bégay,Vince G. Amoroso,Vidya Govind,Richard D. Minshall,Ewan St. John Smith,John Larson,Michael Gotthardt,Stefan Kempa,Gary R. Lewin,Gary R. Lewin +25 more
TL;DR: The metabolic rewiring of glycolysis can circumvent the normally lethal effects of oxygen deprivation, a mechanism that could be harnessed to minimize hypoxic damage in human disease.
Journal ArticleDOI
Naked Mole-Rats: Blind, Naked, and Feeling No Pain.
TL;DR: The naked mole‐rat may be an extreme model of adaptation to subterranean life and provides insights into the complex interplay of evolutionary adaptations to the constraints of subterranean living.
Journal ArticleDOI
Altered cochlear innervation in developing and mature naked and Damaraland mole rats
Catherine M. Barone,Sytse Douma,Daniël O. J. Reijntjes,Brigitte M. Browe,Christine Köppl,Georg M. Klump,Thomas J. Park,Sonja J. Pyott +7 more
TL;DR: Differences in cochlear innervation specifically between the two subterranean rodents and more broadly among rodents provides insight into the coChlear mechanisms that enhance frequency sensitivity and sound localization, maturation of the auditory system, and the evolutionary adaptations occurring in response to subterranean environments.
Journal ArticleDOI
The naked mole-rat has a functional purinergic pain pathway despite having a non-functional peptidergic pain pathway.
Brigitte M. Browe,Abigail R. Olsen,Cesar Ramirez,Rebecca H. Rickman,Ewan St. John Smith,Thomas J. Park +5 more
TL;DR: It is established that the purinergic C-fiber pathway is present and functional in naked mole-rats and that cannabinoid-mediated analgesia occurs in this species.
Book ChapterDOI
Sensory Systems of the African Naked Mole-Rat.
Emily N. Vice,Samantha Lagestee,Brigitte M. Browe,Deblina Deb,Ewan St. John Smith,Thomas J. Park +5 more
TL;DR: Naked mole-rats share some sensory characteristics with other subterraneans, including lack of object vision, retention of the ability to entrain their circadian rhythm to light, and poor hearing as mentioned in this paper.