B
Bushra Khursheed
Researcher at Howard Hughes Medical Institute
Publications - 1
Citations - 788
Bushra Khursheed is an academic researcher from Howard Hughes Medical Institute. The author has contributed to research in topics: Receptor & Hsp90. The author has an hindex of 1, co-authored 1 publications receiving 764 citations.
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Reduced levels of hsp90 compromise steroid receptor action in vivo
Didier Picard,Bushra Khursheed,Michael J. Garabedian,Marc G. Fortin,Marc G. Fortin,Susan Lindquist,Keith R. Yamamoto +6 more
TL;DR: This work has taken advantage of the capacity of mammalian steroid receptors to function in yeast and constructed a strain of Saccharomyces cerevisiae in which hsp90 expression was regulatable and could be reduced more than 20-fold relative to wild type, providing the first biological evidence that hSp90 acts in the signal transduction pathway for steroid receptors.