C
C. Gopi Mohan
Researcher at Amrita Institute of Medical Sciences and Research Centre
Publications - 58
Citations - 1500
C. Gopi Mohan is an academic researcher from Amrita Institute of Medical Sciences and Research Centre. The author has contributed to research in topics: Virtual screening & Docking (molecular). The author has an hindex of 20, co-authored 52 publications receiving 1214 citations. Previous affiliations of C. Gopi Mohan include University of Bath & Amrita Vishwa Vidyapeetham.
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Antibiotic resistance in Pseudomonas aeruginosa and alternative therapeutic options.
TL;DR: This review is intended to raise awareness of several novel approaches that can be considered further for combating drug resistant P. aeruginosa infections.
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Antiobesity and lipid lowering effects of Glycyrrhiza chalcones: experimental and computational studies.
TL;DR: The results indicate the potential of the chalcone scaffold as a source of PL inhibitors for preventing obesity and the antiobesity and lipid lowering effects of 7 and 10 in high fat diet (HFD) fed male SD rats.
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Synthesis, biological evaluation and molecular modeling study of pyrazole derivatives as selective COX-2 inhibitors and anti-inflammatory agents
Ashish Kumar Tewari,Ved Prakash Singh,Pratima Yadav,Garima Gupta,Amit Kumar Singh,Raj Kumar Goel,Pravin S. Shinde,C. Gopi Mohan +7 more
TL;DR: A novel series of pyrazole derivatives were synthesized and evaluated in vivo for their anti- inflammatory activity in carrageenan-induced rat paw edema model and showed comparable anti-inflammatory activity to Nimesulide, the standard drug taken for the studies.
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Inhibition of Acetylcholinesterase by Coumarins: The Case of Coumarin 106
Adyary Fallarero,Päivi P. Oinonen,Shikhar Gupta,Pia Blom,Anna Galkin,C. Gopi Mohan,Pia Vuorela +6 more
TL;DR: This is the first report where AChE inhibitory activity has been associated with coumarin 106, and proof has been given of its convenience as a lead molecule.
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Crystal structure of protoporphyrinogen oxidase from Myxococcus xanthus and its complex with the inhibitor acifluorfen
Hazel R. Corradi,Anne V. Corrigall,Ester Boix,C. Gopi Mohan,Edward D. Sturrock,P.N. Meissner,K. Ravi Acharya +6 more
TL;DR: There is a discrepancy between the dimerization state of the protein in solution and in the crystal, and conserved structural features are discussed in relation to a number of South African variegate porphyria-causing mutations in the human enzyme.