R
Raja Biswas
Researcher at Amrita Institute of Medical Sciences and Research Centre
Publications - 115
Citations - 5491
Raja Biswas is an academic researcher from Amrita Institute of Medical Sciences and Research Centre. The author has contributed to research in topics: Staphylococcus aureus & Peptidoglycan. The author has an hindex of 35, co-authored 107 publications receiving 4395 citations. Previous affiliations of Raja Biswas include University of Tübingen & Amrita Vishwa Vidyapeetham.
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Journal ArticleDOI
Suicidal erythrocyte death in sepsis
Daniela S. Kempe,Ahmad Akel,Philipp A. Lang,Tobias Hermle,Raja Biswas,Juliana Muresanu,Björn Friedrich,Peter Dreischer,Christiane Wolz,Ulrike Schumacher,Andreas Peschel,Friedrich Götz,Gerd Döring,Thomas Wieder,Erich Gulbins,Florian Lang +15 more
TL;DR: A novel pathophysiological mechanism leading to anemia and derangement of microcirculation during sepsis is disclosed, including exposure to plasma from septic patients triggers phosphatidylserine exposure leading to adherence to the vascular wall and clearance from circulating blood.
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Bacteria-derived Peptidoglycans Constitute Pathogen-associated Molecular Patterns Triggering Innate Immunity in Arabidopsis
Andrea A. Gust,Raja Biswas,Heike D. Lenz,Thomas Rauhut,Stefanie Ranf,Birgit Kemmerling,Friedrich Götz,Erich Glawischnig,Justin Lee,Georg Felix,Thorsten Nürnberger +10 more
TL;DR: It is proposed that PGN perception systems arose independently in both lineages and are the result of convergent evolution, and it is shown that both PAMPs are perceived via different perception systems.
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Activity of the major staphylococcal autolysin Atl
TL;DR: An atlA deletion mutant is created in S. aureus that formed large cell clusters and was biofilm-negative, and the first evidence that the amidase indeed cleaves the amide bond between N-acetyl muramic acid and L-alanine is provided.
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Role of staphylococcal wall teichoic acid in targeting the major autolysin Atl.
Martin Schlag,Raja Biswas,Bernhard Krismer,Thomas P. Kohler,Sebastian Zoll,Wenqi Yu,Heinz Schwarz,Andreas Peschel,Friedrich Götz +8 more
TL;DR: It is shown that targeting of the amidase repeats is based on an exclusion strategy mediated by wall teichoic acid (WTA), and by preventing binding of Atl, WTA directs Atl to the cross‐wall to perform the last step of cell division, namely separation of the daughter cells.
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Chitosan-hyaluronic acid/nano silver composite sponges for drug resistant bacteria infected diabetic wounds
TL;DR: The results suggest that this nanocomposite sponges could be used as a potential material for wound dressing for DFU infected with antibiotic resistant bacteria if the optimal concentration of nAg exhibiting antibacterial action with least toxicity towards mammalian cells is identified.