P
Pia Vuorela
Researcher at University of Helsinki
Publications - 162
Citations - 7514
Pia Vuorela is an academic researcher from University of Helsinki. The author has contributed to research in topics: Biofilm & Peucedanum palustre. The author has an hindex of 39, co-authored 162 publications receiving 6813 citations. Previous affiliations of Pia Vuorela include Åbo Akademi University.
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Journal ArticleDOI
Antimicrobial effects of Finnish plant extracts containing flavonoids and other phenolic compounds
Jussi-Pekka Rauha,Susanna Remes,Marina Heinonen,Anu Hopia,Marja P Kähkönen,Tytti S. Kujala,Kalevi Pihlaja,Heikki Vuorela,Pia Vuorela +8 more
TL;DR: Flavone, quercetin and naringenin were effective in inhibiting the growth of the organisms and purple loosestrife was the most active plant extracts against gram-positive Staphylococcus aureus.
Journal ArticleDOI
Anti-Inflammatory Effects of Flavonoids: Genistein, Kaempferol, Quercetin, and Daidzein Inhibit STAT-1 and NF-κB Activations, Whereas Flavone, Isorhamnetin, Naringenin, and Pelargonidin Inhibit only NF-κB Activation along with Their Inhibitory Effect on iNOS Expression and NO Production in Activated Macrophages
TL;DR: The effects and mechanisms of naturally occurring phenolic compounds on iNOS expression and NO production in activated macrophages partially explain the pharmacological efficacy of flavonoids as anti-inflammatory compounds.
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Antimicrobial activity of some coumarin containing herbal plants growing in Finland.
Tiina Ojala,Susanna Remes,Pasi Haansuu,Heikki Vuorela,Raimo Hiltunen,Kielo Haahtela,Pia Vuorela +6 more
TL;DR: Sensitivity to methanol extracts was found to vary considerably among the micro-organisms, the extract from Petroselinum crispum and Ruta graveolens showing the highest toxicity against Rhizoctonia solani.
Journal ArticleDOI
Natural Products in the Process of Finding New Drug Candidates
Pia Vuorela,Maija Leinonen,Pekka Saikku,Päivi Tammela,Jussi-Pekka Rauha,Tero Wennberg,Heikki Vuorela +6 more
TL;DR: The detection of natural compounds active against C. pneumoniae is presented as an example and can be guided by epidemiologic studies facilitated with computer assisted HPLC microfractionation and microplate technology.
Journal ArticleDOI
Ethnobotanical and antimicrobial investigation on some species of Terminalia and Combretum (Combretaceae) growing in Tanzania.
TL;DR: The results of the antimicrobial screening support the ethnomedical uses of these plants, which have medical applications against various bacterial infections, and against symptoms like diarrhoea, hypertension and even cancer.