C
C. R. Petrie
Researcher at Brigham Young University
Publications - 12
Citations - 364
C. R. Petrie is an academic researcher from Brigham Young University. The author has contributed to research in topics: Ribonucleoside & Nucleoside. The author has an hindex of 8, co-authored 12 publications receiving 355 citations.
Papers
More filters
Journal ArticleDOI
Synthesis and biological activity of 6-azacadeguomycin and certain 3,4,6-trisubstituted pyrazolo[3,4-d]pyrimidine ribonucleosides.
TL;DR: Among these compounds, the guanosine analogues 7a and 20a showed significant activity against measles in vitro and were found to exhibit moderate antitumor activity in vitro against L1210 and P388 leukemia.
Journal ArticleDOI
Synthesis and biological activity of certain 3,4-disubstituted pyrazolo[3,4-d]pyrimidine nucleosides.
Howard B. Cottam,C. R. Petrie,P. A. Mckernan,Richard J. Goebel,N. K. Dalley,R. B. Davidson,Roland K. Robins,G. R. Revankar +7 more
TL;DR: 3-Bromoallopur inol ribonucleoside (6a) was found to be more active than allopurinol ribonside against Leishmania tropica within human macrophages in vitro and exhibited the most significant broad-spectrum in vitro antiviral and antitumor activity.
Journal ArticleDOI
Novel pyrazolo[3,4-d]pyrimidine nucleoside analog with broad-spectrum antiviral activity.
Donald F. Smee,P. A. Mckernan,L D Nord,R C Willis,C. R. Petrie,T M Riley,Ganapathi R. Revankar,Roland K. Robins,R A Smith +8 more
TL;DR: Exogenous uridine was able to reverse the virus-inhibitory effects of the compound, leading to the discovery that N10169 5'-monophosphate is a potent inhibitor of cellular orotidylate decarboxylase.
Journal ArticleDOI
Synthesis, intramolecular hydrogen bonding, and biochemical studies of clitocine, a naturally occurring exocyclic amino nucleoside.
R. J. Moss,C. R. Petrie,Rich B. Meyer,L D Nord,Randall C. Willis,Roberts A. Smith,Steven B. Larson,Ganesh D. Kini,Roland K. Robins +8 more
TL;DR: The total synthesis of clitocine [6-amino-5-nitro-4-(beta-D-ribofuranosylamino)pyrimidine] (1), a nucleoside recently isolated from the mushroom Clitocybe inversa, has been accomplished.
Journal ArticleDOI
Synthesis and biological activity of certain nucleoside and nucleotide derivatives of pyrazofurin.
C. R. Petrie,G. R. Revankar,N. K. Dalley,R. D. George,P. A. Mckernan,R. L. Hamill,Roland K. Robins +6 more
TL;DR: A number of nucleoside and nucleotide derivatives of 4-hydroxy-3-beta-D-ribofuranosylpyrazole-5-carboxamide and pyrazofurin were prepared and tested for their antiviral and cytostatic activity in cell culture and exhibited significant inhibitory effects on the growth of L1210 and P388 leukemias and Lewis lung carcinoma cells in vitro.