C
C. S. Ricard
Researcher at Wadsworth Center
Publications - 2
Citations - 286
C. S. Ricard is an academic researcher from Wadsworth Center. The author has contributed to research in topics: Coronavirus & Gene. The author has an hindex of 2, co-authored 2 publications receiving 279 citations.
Papers
More filters
Journal ArticleDOI
Proteolytic cleavage of the E2 glycoprotein of murine coronavirus: activation of cell-fusing activity of virions by trypsin and separation of two different 90K cleavage fragments.
TL;DR: The cell-fusing activity of a coronavirus required proteolytic cleavage of the E2 glycoprotein, either by the addition of a protease to virions or by cellular proteases acting on E2, which was transported to the plasma membrane during virus maturation.
Book ChapterDOI
Temperature-Sensitive Mutants of MHV-A59
L. S. Sturman,C. Eastwood,Mark F. Frana,Cynthia S. Duchala,F. Baker,C. S. Ricard,Stanley G. Sawicki,Kathryn V. Holmes +7 more
TL;DR: The next goal will be to understand the interactions of viral macromolecules during coronavirus replication, and to identify domains on the viral proteins which are responsible for these molecular interactions.