Camila Rodrigues

TL;DR: The hypothesis is that genetic polymorphisms are associated with RBC alloimmunization among patients with sickle cell disease and this could lead to new treatments for SCD.

TL;DR: Molecular matching for C, c, E, e, K was able to reduce RBC alloimmunisation in MDS patients and an over-representation of the HLA-DRB1*13 allele in the non-alloimmunised group of patients with MDS.

TL;DR: The aim of this study was to conduct a literature review to assess the influence of genetic factors of immune response genes, especially genes of the major histocompatibility complex and cytokines, which may be related to the development of factor VIII inhibitors in hemophilia A patients.

TL;DR: Red blood cell (RBC) alloimmunisation is an event that may occur due to factors such as numerous blood transfusions, age, gender and genetic factorssuch as human leukocyte antigen (HLA).

TL;DR: The data has demonstrated that the polymorphisms on TNF-238 GA, T NF-308 GA were associated to MPN development in this population, triggered by JAK2 V617F mutation.