The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis

Solvent content of protein crystals.

Publisher Summary This chapter describes the advances with an emphasis on the structures of the alcohol dehydrogenases and the relationship between structure and function Yeast and mammalian alcohol dehydrogenase differ in substrate specificity and rate of catalytic activity The classic yeast enzyme is more specific for acetaldehyde and ethanol, which is consistent with its recognized physiological Significance to participate in alcohol fermentation at the end of the glycolytic pathway Enzyme forms with other functions and properties also occur in yeast The mammalian enzymes have broad substrate specificity and, even with primary alcohols, the maximum activity is not observed with ethanol Alcohols including ethanol, produced in the intestinal tracts mainly by bacterial actions, are found in the portal vein One physiological function of liver alcohol dehydrogenase may be to metabolize these products Structural studies have established that mammalian alcohol dehydrogenases have a distant evolutionary link to both the yeast and bacterial enzymes Ingested alcohol is metabolized to acetaldehyde mainly by the action of liver alcohol dehydrogenase

3 Alcohol Dehydrogenases

Three-dimensional structure of horse liver alcohol dehydrogenase at 2.4 Å resolution

Thiolato-complexes of the transition metals

/pdf/the-crystal-structures-of-the-adducts-sbcl5-pocl3-sbcl5-ch3-1bilyk3fd7.pdf

The Crystal Structures of the Adducts SbCl5.POCl3, SbCl5.(CH3)3PO, and NbCl5.POCl3.

/pdf/crystallization-of-horse-liver-alcohol-dehydrogenase-chfxbdcifs.pdf

Crystallization of horse liver alcohol dehydrogenase complexes from alcohol solutions

/pdf/the-crystal-structure-of-sncl4-2pocl3-4p0fb3qxec.pdf

The Crystal Structure of SnCl4.2POCl3.

/pdf/the-crystal-structure-of-ticl4-pocl3-2-4rey7zteg1.pdf

The Crystal Structure of (TiCl4.POCl3)2.

/pdf/evidence-of-a-branched-chain-reaction-in-the-oscillating-57aqba1s47.pdf

Carl-Ivar Brändén

Papers

The Crystal Structures of the Adducts SbCl5.POCl3, SbCl5.(CH3)3PO, and NbCl5.POCl3.

Crystallization of horse liver alcohol dehydrogenase complexes from alcohol solutions

The Crystal Structure of SnCl4.2POCl3.

The Crystal Structure of (TiCl4.POCl3)2.

Evidence of a Branched Chain Reaction in the Oscillating Reaction of Hydrogen Peroxide, Iodine, and Iodate.