The present invention is directed to in vitro methods for determining the fitness of a subject based on the determination of the expression levels of different genes The invention also provides an in vitro method for selecting a subject as having a fitness level suitable to participate in an endurance sport, for monitoring the response to training of a subject during an endurance exercise training and for selecting a personalized training program aimed at improving fitness of a subject, based on the determination of the expression levels of said genes, as well as a kit comprising reagents for determining said expression levels and the use thereof, a computer program and a computer-implemented method

Genetic biomarker profiles for endurance sport suitability

Barriers & facilitators to physical activity in people with depression and type 2 diabetes mellitus in Pakistan: A qualitative study to explore perspectives of patient participants, carers and healthcare staff

According to a composition and a kit for predicting or diagnosing sensitivity to exercise, each comprising a polynucleotide capable of detecting a single nucleotide polymorphism marker, and a method for providing information for predicting or diagnosing sensitivity of a subject to exercise, a degree of decrease in body mass index with the exercise of the subject can be predicted or measured. The predicted or measured degree of decrease in body mass index with the exercise of the subject can be applied to personalized treatment for obesity to increase therapeutic effects.

Composition and kit for predicting sensitivity to exercise and method using same

A set of biomarkers have been identified that allows one to predict subjects who will respond to an exercise regime in term of cardiorespiratory fitness as assessed by maximal oxygen uptake. These predictions may be used, for example, to predict risk of cardiovascular disease, to design a more effective program for cardiac rehabilitation, to predict capacity for athletic performance or physically demanding occupation, and to predict ability to maintain functional capacity with aging using exercise.

Predictive Biomarkers for Response to Exercise

Physical inactivity is recognised as a major public health problem. In Sweden about 1/3 of the adult population reports being insufficiently active. A central task in public health work is to support the individual, without blaming, in making healthy choices. Initiatives in healthcare, such as counselling on physical activity, have been shown to be both cost-effective and effective for disease prevention and treatment. The use of a physical activity vital sign and brief advice from physicians can make a big difference. In this paper we present how the healthcare system as one of eight evidence-based investments can promote physical activity. The eight investment areas are: whole-of-school programs, active transport, active urban design, health care, public education, sports and recreation, workplaces and community-wide programs. Evidence suggests that the largest population health benefit will be achieved by combining these investments and implementing a systems-based approach.

Carl Johan Sundberg

Papers

Predictive Biomarkers for Response to Exercise

[The healthcare system plays a key role in promoting physical acitivity].