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Showing papers by "Carlos Cativiela published in 2019"


Journal ArticleDOI
TL;DR: In this paper, the COST program under the CA15106 (CHAOS, C-H Activation in Organic Synthesis) grant was used to support the work of the reference group Aminoacidos y Peptidos.
Abstract: C. C. and E. P. U. thank the Gobierno de Aragon–Fondo Social Europeo (Spain, reference group Aminoacidos y Peptidos E19_17R) for financial support and the Servicio General de Apoyo a la Investigacion–SAI, Universidad de Zaragoza. E. P. U. thanks the COST program under the CA15106 (CHAOS, C–H Activation in Organic Synthesis) grant.

7 citations


Journal ArticleDOI
TL;DR: Non-hydrated organic solutions of a diphenylalanine amphiphile blocked at the C-terminus with a fluorenylmethyl ester and stabilized at the N-terminal with a trifluoroacetate have been used to prepare amyloid fibrils.

4 citations


Journal ArticleDOI
TL;DR: In this paper, the Spanish Ministerio de Economia y Competitividad (MINECO) (project number CTQ2016-76155•R), by the Fondos Europeos para el Desarrollo Regional (FEDER) and the Gobierno de Aragon (Group E34_R17; Zaragoza, Spain, Biological and Computational Chemistry Group, BCC).

3 citations


Journal ArticleDOI
TL;DR: In this article, C.C.J.-A.M. thanks the Gobierno de Aragon-FSE for predoctoral grant and CTQ2016-76155-R to P.M., thanks the Ministerio de Economia y Competitividad.

2 citations


Journal ArticleDOI
TL;DR: The synthesis of dehydrophos derivatives featuring modified peptide chains, characterized by the presence of substituents in the vinyl moiety, or possessing a phosphonic acid monoalkyl esters other than the monomethyl ester one, has been accomplished by a versatile procedure based on Horner-Wadsworth-Emmons olefination with suitable aldehydes and on the selective hydrolysis of the dialkyl phosphonate group.
Abstract: The synthesis of dehydrophos derivatives featuring modified peptide chains, characterized by the presence of substituents in the vinyl moiety, or possessing a phosphonic acid monoalkyl ester other than the monomethyl ester one, has been accomplished by a versatile procedure based on Horner–Wadsworth–Emmons olefination with suitable aldehydes and on the selective hydrolysis of the dialkyl phosphonate group. Such derivatives have been tested against a series of bacterial strains, using the naturally occurring peptide, dehydrophos, for comparison. Thus, the effects of the aforementioned structural variations on antimicrobial activity have been studied.

1 citations