C
Carlos M. Morel
Researcher at Oswaldo Cruz Foundation
Publications - 110
Citations - 6195
Carlos M. Morel is an academic researcher from Oswaldo Cruz Foundation. The author has contributed to research in topics: Trypanosoma cruzi & Kinetoplast. The author has an hindex of 43, co-authored 100 publications receiving 5812 citations. Previous affiliations of Carlos M. Morel include World Health Organization & National Institute of Standards and Technology.
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In vitro differentiation of Trypanosoma cruzi under chemically defined conditions
TL;DR: Metacyclic trypomastigotes of Trypanosoma cruzi obtained in chemically defined axenic culture are resistant to complement lysis and to macrophage digestion and are able to infect mice with an efficiency similar to that obtained for natural metacyclo-trypomastsigotes obtained from triatomine excreta.
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Strains and clones of Trypanosoma cruzi can be characterized by pattern of restriction endonuclease products of kinetoplast DNA minicircles.
TL;DR: It is shown that, from a given T. cruzi strain, clones with different biological properties can be isolated and identified by their restriction patterns.
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The Global Virome Project
Dennis Carroll,Peter Daszak,Nathan D. Wolfe,George F. Gao,Carlos M. Morel,Subhash Morzaria,Ariel Pablos-Méndez,Oyewale Tomori,Jonna A. K. Mazet +8 more
TL;DR: A Global Virome Project aimed to launch in 2018 that will help identify the bulk of this viral threat and provide timely data for public health interventions against future pandemics is described.
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Sensitive detection and schizodeme classification of Trypanosoma cruzi cells by amplification of kinetoplast minicircle DNA sequences: use in diagnosis of Chagas' disease
TL;DR: This method should prove useful as a rapid, specific and sensitive assay for Chagas' disease in chronic patients as well as for epidemiological studies of infected animals and insects.
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Use of a Simplified Polymerase Chain Reaction Procedure to Detect Trypanosoma cruzi in Blood Samples from Chronic Chagasic Patients in a Rural Endemic Area
Patrick Wincker,Constança Britto,José Borges Pereira,M. A. Cardoso,Walter Oelemann,Carlos M. Morel +5 more
TL;DR: The results suggest that the PCR may be a useful complement to serology in the diagnosis of Chagas' disease, and that it is the most powerful technique available for parasite detection in patients with chronic disease.