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Caroline A. Abbott
Researcher at Manchester Metropolitan University
Publications - 56
Citations - 6795
Caroline A. Abbott is an academic researcher from Manchester Metropolitan University. The author has contributed to research in topics: Diabetes mellitus & Diabetic neuropathy. The author has an hindex of 30, co-authored 55 publications receiving 6247 citations. Previous affiliations of Caroline A. Abbott include University of Manchester & John Radcliffe Hospital.
Papers
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Journal ArticleDOI
The North-West Diabetes Foot Care Study: incidence of, and risk factors for, new diabetic foot ulceration in a community-based patient cohort.
Caroline A. Abbott,Anne L. Carrington,H. Ashe,S. Bath,L. C. Every,Joan Griffiths,A. W. Hann,A. Hussein,Nicky Jackson,Kurt E. Johnson,C. H. Ryder,R. Torkington,E. R. E. Van Ross,A. M. Whalley,P. Widdows,S. Williamson,Andrew J.M. Boulton +16 more
TL;DR: This large cohort study aims to determine the incidence of, and clinically relevant risk factors for, new foot ulceration in a large cohort of diabetic patients in the community healthcare setting.
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Protection of low-density lipoprotein against oxidative modification by high-density lipoprotein associated paraoxonase
TL;DR: A direct role for HDL in preventing atherosclerosis probably by an enzymic process which prevents the accumulation of lipid peroxides on LDL is suggested.
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Prevalence and characteristics of painful diabetic neuropathy in a large community-based diabetic population in the U.K.
TL;DR: One-third of all community-based diabetic patients have painful neuropathic symptoms, regardless of their neuropathic deficit, which highlights a significant morbidity due to painful neuropathy and identifies key groups who warrant screening for PDN.
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Corneal confocal microscopy: a non-invasive surrogate of nerve fibre damage and repair in diabetic patients
Rayaz A. Malik,Panagiotis A. Kallinikos,Caroline A. Abbott,C. H. M. van Schie,Philip B. Morgan,Nathan Efron,Andrew J.M. Boulton +6 more
TL;DR: In this article, the ability of confocal microscopy to quantify the extent of degeneration and regeneration of corneal nerve fibres in diabetic patients with increasing neuropathic severity was defined.
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Serum Paraoxonase Activity, Concentration, and Phenotype Distribution in Diabetes Mellitus and Its Relationship to Serum Lipids and Lipoproteins
TL;DR: The results indicate that the low paraoxonase activity in diabetes is due to decreased specific activity and suggest an association with peripheral neuropathy, which could be due to reduced capacity to detoxify lipid peroxides in diabetes.