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Caroline B. Michielse
Researcher at University of Amsterdam
Publications - 18
Citations - 2179
Caroline B. Michielse is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Agrobacterium & Fusarium oxysporum. The author has an hindex of 17, co-authored 18 publications receiving 1927 citations. Previous affiliations of Caroline B. Michielse include Leiden University & Radboud University Nijmegen.
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Journal ArticleDOI
Pathogen profile update: Fusarium oxysporum
TL;DR: More than 120 different formae speciales have been identified based on specificity to host species belonging to a wide range of plant families as mentioned in this paper, which can cause severe losses in many vegetables and flowers, field crops, such as cotton, and plantation crops such as banana, date palm and oil palm.
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Agrobacterium -mediated transformation as a tool for functional genomics in fungi
TL;DR: The potential of the Agrobacterium DNA transfer system to be used as a tool for targeted and random mutagenesis in fungi is discussed.
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Agrobacterium -mediated transformation of the filamentous fungus Aspergillus awamori
TL;DR: An efficient protocol for AMT of Aspergillus awamori is described, which has been used to determine the function of Agrobacterium virulence genes during AMT, to identify factors influencing transformation frequencies, to generate insertional mutants and to generate A. Awamori gene knockout transformants.
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Intragenic deletion in the LARGE gene causes Walker-Warburg syndrome.
Jeroen van Reeuwijk,Prabhjit K. Grewal,Prabhjit K. Grewal,Mustafa A. Salih,Daniel Beltrán-Valero de Bernabé,Daniel Beltrán-Valero de Bernabé,Jenny M. McLaughlan,Caroline B. Michielse,Caroline B. Michielse,Ralf Herrmann,Jane E. Hewitt,Alice Steinbrecher,Mohamed Z. Seidahmed,Mohamed M. Shaheed,Abdullah Abomelha,Han G. Brunner,Hans van Bokhoven,Thomas Voit +17 more
TL;DR: A 63-kb intragenic LARGE deletion in a family with Walker-Warburg syndrome (WWS), which is characterized by CMD, and severe structural brain and eye malformations, demonstrates that LARGE gene mutations can give rise to a wide clinical spectrum, similar to other genes that have a role in the post-translational modification of the α-dystroglycan protein.
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The nuclear protein Sge1 of Fusarium oxysporum is required for parasitic growth.
Caroline B. Michielse,Ringo van Wijk,Linda Reijnen,Erik M. M. Manders,Sonja Boas,Chantal Olivain,Claude Alabouvette,Martijn Rep +7 more
TL;DR: In this paper, the authors identified a homolog of a master regulator of morphological switch in the plant pathogenic fungus Fusarium oxysporum f. lycopersici, which causes vascular wilt disease in tomato by penetrating the plant roots and colonizing the vascular tissue.