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Cecilia Lai
Researcher at University College London
Publications - 1
Citations - 270
Cecilia Lai is an academic researcher from University College London. The author has contributed to research in topics: Gene & Gene mapping. The author has an hindex of 1, co-authored 1 publications receiving 256 citations.
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The chromosome 6p22 haplotype associated with dyslexia reduces the expression of KIAA0319, a novel gene involved in neuronal migration
Silvia Paracchini,Ankur M Thomas,Sandra Castro,Cecilia Lai,Murugan Paramasivam,Yu Wang,Brendan J. Keating,Jennifer M. Taylor,Douglas F. Hacking,Thomas S. Scerri,Clyde Francks,Alex J. Richardson,Richard Wade-Martins,John F. Stein,Julian C. Knight,Andrew J. Copp,Joseph J. LoTurco,Anthony P. Monaco +17 more
TL;DR: The data suggest a direct link between a specific genetic background and a biological mechanism leading to the development of dyslexia: the risk haplotype on chromosome 6p22.2 down-regulates the KIAA0319 gene which is required for neuronal migration during the formation of the cerebral neocortex.