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Richard Wade-Martins

Researcher at University of Oxford

Publications -  189
Citations -  16535

Richard Wade-Martins is an academic researcher from University of Oxford. The author has contributed to research in topics: Gene & Parkinson's disease. The author has an hindex of 51, co-authored 170 publications receiving 12347 citations. Previous affiliations of Richard Wade-Martins include Wellcome Trust Centre for Human Genetics & Harvard University.

Papers
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Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model

Javier Alegre-Abarrategui, +6 more
- 01 Nov 2009 - 
TL;DR: The functional involvement of LRRK2 in the endosomal-autophagic pathway and the recruitment to specific membrane microdomains in a physiological human gene expression model is demonstrated suggesting a novel function for this important PD-related protein.
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Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease.

Brent J. Ryan, +3 more
- 01 Apr 2015 - 
TL;DR: How recent advances in understanding familial PD-associated proteins have identified novel mechanisms and therapeutic strategies for addressing mitochondrial dysfunction in PD is highlighted.
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The Role of Astrocyte Dysfunction in Parkinson’s Disease Pathogenesis

Heather D.E. Booth, +2 more
- 01 Jun 2017 - 
TL;DR: Recent studies have determined that genes known to have a causative role in the development of PD are expressed inAstrocytes and have important roles in astrocyte function, and their impact on understanding of the pathophysiology of PD is discussed.