C
Changxiong Guo
Researcher at Southern Illinois University School of Medicine
Publications - 1
Citations - 184
Changxiong Guo is an academic researcher from Southern Illinois University School of Medicine. The author has contributed to research in topics: Retinoid X receptor & Pregnane X receptor. The author has an hindex of 1, co-authored 1 publications receiving 163 citations.
Papers
More filters
Journal ArticleDOI
Nuclear receptors in the multidrug resistance through the regulation of drug-metabolizing enzymes and drug transporters.
TL;DR: PXR/CAR expression levels and/or activation statuses may predict prognosis and identify the risk of drug resistance in patients subjected to chemotherapy, and PXR-CAR antagonists, when used in combination with existing chemotherapeutics that activate PXr/CAR, are feasible and promising options that could be utilized to overcome or, at least, attenuate MDR in cancer cells.