C
Chao-Hung Wang
Researcher at Memorial Hospital of South Bend
Publications - 150
Citations - 7393
Chao-Hung Wang is an academic researcher from Memorial Hospital of South Bend. The author has contributed to research in topics: Heart failure & Endothelial stem cell. The author has an hindex of 31, co-authored 145 publications receiving 6779 citations. Previous affiliations of Chao-Hung Wang include St. Michael's GAA, Sligo & National Yang-Ming University.
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Journal ArticleDOI
A Self-Fulfilling Prophecy C-Reactive Protein Attenuates Nitric Oxide Production and Inhibits Angiogenesis
Subodh Verma,Chao-Hung Wang,Shu-Hong Li,Aaron S. Dumont,Paul W.M. Fedak,Mitesh V. Badiwala,Bikramjit Dhillon,Richard D. Weisel,Ren-Ke Li,Donald A.G. Mickle,Duncan J. Stewart +10 more
TL;DR: CRP, at concentrations known to predict adverse vascular events, directly quenches the production of the NO, in part, through posttranscriptional effect on eNOS mRNA stability, which may facilitate the development of diverse cardiovascular diseases.
Journal ArticleDOI
New markers of inflammation and endothelial cell activation: Part I.
Paul E. Szmitko,Chao-Hung Wang,Richard D. Weisel,John R. de Almeida,Todd J. Anderson,Subodh Verma +5 more
TL;DR: This review article will provide a brief overview of the link between inflammation, endothelial dysfunction, and atherosclerosis and will begin highlighting emerging inflammatory mediators of endothelial cell (EC) activation, a discussion that will be continued in Part 2.
Journal ArticleDOI
Resistin Promotes Endothelial Cell Activation Further Evidence of Adipokine-Endothelial Interaction
Subodh Verma,Shu-Hong Li,Chao-Hung Wang,Paul W.M. Fedak,Ren-Ke Li,Richard D. Weisel,Donald A.G. Mickle +6 more
TL;DR: The novel adipokine resistin exerts direct effects to promote EC activation by promoting ET-1 release, in part by inducingET-1 promoter activity via the AP-1 site, and may be mechanistically linked to cardiovascular disease in the metabolic syndrome.
Journal ArticleDOI
C-Reactive Protein Attenuates Endothelial Progenitor Cell Survival, Differentiation, and Function Further Evidence of a Mechanistic Link Between C-Reactive Protein and Cardiovascular Disease
Subodh Verma,Michael A. Kuliszewski,Shu Hong Li,Paul E. Szmitko,Liana Zucco,Chao-Hung Wang,Mitesh V. Badiwala,Donald A.G. Mickle,Richard D. Weisel,Paul W.M. Fedak,Duncan J. Stewart,Michael Kutryk +11 more
TL;DR: Human recombinant CRP, at concentrations known to predict adverse vascular outcomes, directly inhibits EPC differentiation, survival, and function, key components of angiogenesis and the response to chronic ischemia.
Journal ArticleDOI
C-Reactive Protein Upregulates Angiotensin Type 1 Receptors in Vascular Smooth Muscle
Chao-Hung Wang,Shu-Hong Li,Richard D. Weisel,Paul W.M. Fedak,Aaron S. Dumont,Paul E. Szmitko,Ren-Ke Li,Donald A.G. Mickle,Subodh Verma +8 more
TL;DR: CRP, at concentrations known to predict cardiovascular events, upregulates AT1-R–mediated atherosclerotic events in vascular smooth muscle in vitro and in vivo, lending credence to the notion that CRP functions as a proatherosclerosis factor as well as a powerful risk marker.