Charles B. Cangro

TL;DR: It is concluded that PVN is a serious hazard for renal transplant recipients and contributes directly to graft loss and antiviral drugs are needed, as the reduction of immunosuppression alone may not significantly improve graft function in patients with already established PVN.

TL;DR: Laroscopic donor nephrectomy appears to be safe and decreases morbidity in the renal donor, and allograft function is comparable to that in open neph rectomy series.

TL;DR: Biopsies showing lesser degrees of renal scarring at the time of diagnosis were associated with, more likely, resolution of the infection, in response to decrease of immunosuppression, and correlated with worse graft outcome.

TL;DR: The structural damage to beta cells demonstrated in this study is similar to morphological and functional abnormalities previously described in experimental animal models and can at least partially account for the glucose metabolism abnormalities seen in patients receiving these drugs.