C
Charles de Mestral
Researcher at University of Toronto
Publications - 105
Citations - 2363
Charles de Mestral is an academic researcher from University of Toronto. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 20, co-authored 77 publications receiving 1689 citations. Previous affiliations of Charles de Mestral include University of Melbourne & Sunnybrook Research Institute.
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Journal ArticleDOI
Flail chest injuries: a review of outcomes and treatment practices from the National Trauma Data Bank
TL;DR: Given the high rates of morbidity and mortality in patients with a flail chest injury, alternate methods of treatment including more consistent use of epidural catheters for pain or surgical fixation need to be investigated with large randomized controlled trials.
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Intracranial Pressure Monitoring in Severe Traumatic Brain Injury: Results from the American College of Surgeons Trauma Quality Improvement Program
Aziz S. Alali,Robert A. Fowler,Todd G. Mainprize,Damon C. Scales,Alexander Kiss,Charles de Mestral,Joel G. Ray,Avery B. Nathens +7 more
TL;DR: In this observational study, intracranial pressure monitoring utilization was associated with lower mortality, however, variability in ICP monitoring rates contributed only modestly to variability in institutional mortality rates.
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Comparative operative outcomes of early and delayed cholecystectomy for acute cholecystitis: a population-based propensity score analysis.
Charles de Mestral,Ori D. Rotstein,Andreas Laupacis,Jeffrey S Hoch,Brandon Zagorski,Aziz S. Alali,Avery B. Nathens +6 more
TL;DR: The benefit of early overdelayed cholecystectomy for patients with acute choleCystitis is supported, with a lower risk of major bile duct injury and a shorter hospital length of stay.
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The mortality benefit of direct trauma center transport in a regional trauma system: a population-based analysis.
Barbara Haas,Therese A. Stukel,David Gomez,Brandon Zagorski,Charles de Mestral,Sunjay V. Sharma,Gordon D. Rubenfeld,Avery B. Nathens +7 more
TL;DR: Although many surviving patients are later transferred to a TC, initial triage to a NTC is associated with at least a 30% increase in mortality in the first 48 hours after injury, which is population-based evidence of the early benefits of direct triages to TC.
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Tracheostomy timing in traumatic brain injury: a propensity-matched cohort study.
Aziz S. Alali,Damon C. Scales,Robert A. Fowler,Todd G. Mainprize,Joel G. Ray,Alexander Kiss,Charles de Mestral,Avery B. Nathens +7 more
TL;DR: In this observational study, early tracheostomy was associated with a shorter duration of mechanical ventilation, intensive care unit stay, and hospital stay but not hospital mortality, suggesting ET may represent a mechanism to reduce in-hospital morbidity for patients with TBI.