C
Charles Kennedy
Researcher at National Institutes of Health
Publications - 54
Citations - 10676
Charles Kennedy is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Cerebral blood flow & Deoxyglucose. The author has an hindex of 29, co-authored 54 publications receiving 10509 citations. Previous affiliations of Charles Kennedy include Georgetown University & United States Public Health Service.
Papers
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Journal ArticleDOI
The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat.
Louis Sokoloff,Martin Reivich,Charles Kennedy,Charles Kennedy,M. H. Des Rosiers,Clifford S. Patlak,Karen D. Pettigrew,O. Sakurada,M. Shinohara +8 more
TL;DR: The method can be applied to most laboratory animals in the conscious state and is based on the use of 2‐deoxy‐D‐[14C]glucose as a tracer for the exchange of glucose between plasma and brain and its phosphorylation by hexokinase in the tissues.
Journal ArticleDOI
Measurement of local cerebral blood flow with iodo [14C] antipyrine
TL;DR: Iodo[14C]antipyrine appears, therefore, to be a satisfactory nonvolatile tracer for the measurement of local cerebral blood flow.
Journal ArticleDOI
Mapping of functional neural pathways by autoradiographic survey of local metabolic rate with (14C)deoxyglucose.
TL;DR: An enzymatic preparation from human brain converts tryptamine to tryptoline (9H-1,2,3, 4-tetrahydropyrido(3,4-b)indole) in the presence of 5-methyltetrahYDrofolic acid, which yields 1- methyltryptoline and 5-hydroxytryptoline, respectively.
Journal ArticleDOI
Metabolic mapping of the primary visual system of the monkey by means of the autoradiographic [14C]deoxyglucose technique
Charles Kennedy,M. H. Des Rosiers,O. Sakurada,M. Shinohara,Martin Reivich,Jane Jehle,Louis Sokoloff +6 more
TL;DR: An autoradiographic technique that employs 2-[14-C]deoxyglucose to measure the local rates of glucose utilization within the brain has been applied to the binocular visual system of the Macaque monkey.