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Charles P. Ordahl
Researcher at University of California, San Francisco
Publications - 68
Citations - 6741
Charles P. Ordahl is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Gene & Myotome. The author has an hindex of 42, co-authored 68 publications receiving 6637 citations. Previous affiliations of Charles P. Ordahl include Centre national de la recherche scientifique.
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Journal ArticleDOI
Transcriptional repression of an embryo-specific muscle gene
Carlin S. Long,Charles P. Ordahl +1 more
TL;DR: Using run-on transcription assays it is demonstrated that the chicken cardiac troponin T (cTNT) gene repression occurs at the level of transcription, indicating that transcriptional as well as post-transcriptional mechanisms operate both to activate and repress gene expression during skeletal muscle development.
Journal ArticleDOI
Asymmetric cell divisions are concentrated in the dermomyotome dorsomedial lip during epaxial primary myotome morphogenesis
TL;DR: The DML environmental niche is sufficient to promote numb expression in epaxial dermomyotome tissue that does not normally express this factor, providing, for the first time, a non-retrospective tracing analysis of the mechanism by which the DML fulfils the stem-cell pool role it plays during Epaxial primary myotome morphogenesis.
Journal ArticleDOI
Precocious terminal differentiation of premigratory limb muscle precursor cells requires positive signalling
Sara J. Venters,Rebecca E. Argent,Fiona M. Deegan,Gina Perez-Baron,Gina Perez-Baron,Ted S. Wong,William E. Tidyman,Wilfred F. Denetclaw,Christophe Marcelle,Marianne Bronner-Fraser,Charles P. Ordahl +10 more
TL;DR: The results support both hypotheses and show further that placing axial structures adjacent to the somite ventrolateral lip induces an axial pattern of myocyte terminal differentiation and elongation.
Journal Article
Single cell analysis of transfected gene expression in primary heart cultures containing multiple cell types.
TL;DR: Immunofluorescence microscopy is used to analyze expression of chloramphenicol acetyltransferase (CAT) on a single cell basis and shows that myocardial cells take up and express transfected DNA approximately 7 times less efficiently than non-myocardIAL cells.
Book ChapterDOI
Developmental regulation of sarcomeric gene expression.
TL;DR: Analysis of muscle gene transcription has advanced to the point, where definitive information is available regarding a number of important muscle-specific cis and trans factors, and the information for additional cis andtrans factors will soon be forthcoming.