C
Charles Y.C. Pak
Researcher at University of Texas Southwestern Medical Center
Publications - 386
Citations - 23880
Charles Y.C. Pak is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Calcium & Hypercalciuria. The author has an hindex of 80, co-authored 386 publications receiving 23097 citations. Previous affiliations of Charles Y.C. Pak include Scott & White Hospital & University of Chicago.
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Journal ArticleDOI
Severely Suppressed Bone Turnover: A Potential Complication of Alendronate Therapy
Clarita V. Odvina,Joseph E. Zerwekh,D. Sudhaker Rao,Naim M. Maalouf,Frank A Gottschalk,Charles Y.C. Pak +5 more
TL;DR: The findings raise the possibility that severe suppression of bone turnover may develop during long-term alendronate therapy, resulting in increased susceptibility to, and delayed healing of, nonspinal fractures, and the need for increased awareness and monitoring.
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The Hypercalciurias CAUSES, PARATHYROID FUNCTIONS, AND DIAGNOSTIC CRITERIA
TL;DR: The results support the proposed mechanisms for the hypercalciuria and provide reliable diagnostic criteria for the various forms of hyperCalciuria.
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A simple test for the diagnosis of absorptive, resorptive and renal hypercalciurias
TL;DR: Of the 28 patients with primary hyperparathyroidism (resorptive hypercalciuria), 25 had hypercalcemia and 21 had high fasting urinary calcium, and six patients with renal hyperCalciuria had normocalcemia, high fasting kidneys, and high-normal fasting urinary cyclic AMP was normal.
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Relationship of Animal Protein-Rich Diet to Kidney Stone Formation and Calcium Metabolism
TL;DR: Urinary crystallization studies revealed that the animal protein diet, when its electrolyte composition and quantity of protein were kept the same as for the vegetarian diet, conferred an increased risk for uric acid stones, but, because of opposing factors, not for calcium oxalate or calcium phosphate stones.
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Association of urinary pH with body weight in nephrolithiasis.
Naim M. Maalouf,Khashayar Sakhaee,Joan H. Parks,Joan H. Parks,Frederic L. Coe,Frederic L. Coe,Beverley Adams-Huet,Beverley Adams-Huet,Charles Y.C. Pak,Charles Y.C. Pak +9 more
TL;DR: The results confirm the previously proposed scheme that obesity may sometimes cause uric acid nephrolithiasis by producing excessively acid urine due to insulin resistance by concluding that urinary pH is inversely related to body weight among patients with stones.