C
Chee Fang Sum
Researcher at Khoo Teck Puat Hospital
Publications - 135
Citations - 3233
Chee Fang Sum is an academic researcher from Khoo Teck Puat Hospital. The author has contributed to research in topics: Type 2 diabetes & Diabetes mellitus. The author has an hindex of 22, co-authored 106 publications receiving 2483 citations. Previous affiliations of Chee Fang Sum include Alexandra Hospital.
Papers
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Journal ArticleDOI
MicroRNA 144 Impairs Insulin Signaling by Inhibiting the Expression of Insulin Receptor Substrate 1 in Type 2 Diabetes Mellitus
Dwi Setyowati Karolina,Arunmozhiarasi Armugam,Subramaniam Tavintharan,Michael T. K. Wong,Su Chi Lim,Chee Fang Sum,Kandiah Jeyaseelan,Kandiah Jeyaseelan +7 more
TL;DR: It is demonstrated that peripheral blood microRNAs can be developed as unique biomarkers that are reflective and predictive of metabolic health and disorder.
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Lower circulating irisin is associated with type 2 diabetes mellitus.
Jianjun Liu,Melvin D.S. Wong,Wan Ching Toy,Clara Si Hua Tan,Sylvia Liu,Xiao Wei Ng,Subramaniam Tavintharan,Chee Fang Sum,Su Chi Lim +8 more
TL;DR: Plasma irisin levels appear to be associated with important metabolic factors in non-diabetic subjects but not in individuals with type 2 diabetes.
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Circulating miRNA Profiles in Patients with Metabolic Syndrome
Dwi Setyowati Karolina,Subramaniam Tavintharan,Arunmozhiarasi Armugam,Sugunavathi Sepramaniam,Sharon Li Ting Pek,Michael T. K. Wong,Su Chi Lim,Chee Fang Sum,Kandiah Jeyaseelan,Kandiah Jeyaseelan +9 more
TL;DR: Significant dysregulation of seven candidate microRNAs has been found to be associated with risks involved in the manifestation of metabolic syndrome and six of them were identified as potential contributors of dyslipidemia in metabolic syndrome.
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Metabolic signature shift in type 2 diabetes mellitus revealed by mass spectrometry-based metabolomics.
TL;DR: Compared to healthy controls, those with IFG and type 2 diabetes had significantly raised fructose, α-hydroxybutyrate, alanine, proline, phenylalanine, glutamine, branched-chain amino acids, low carbon number lipids, and significantly reduced pyroglutamic acid, glycerophospohlipids,
Journal ArticleDOI
The role of triglyceride glucose index in development of Type 2 diabetes mellitus
Serena Low,Kay Chin Jonathon Khoo,Bastari Irwan,Chee Fang Sum,Tavintharan Subramaniam,Su Chi Lim,Su Chi Lim,Tack Keong Michael Wong +7 more
TL;DR: TyG is potentially useful for predicting Type 2 Diabetes Mellitus in clinical practice and is a potential mediator of association between BMI and T2DM development.